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Garcinol

Inh 78824-30-3
N° du produit ABIN7233254
  • Application
    Inhibition (Inh)
    Fonction
    HAT inhibitor
    Attributs du produit
    Garcinol is a HAT (histone acetyltransferase) inhibitor (p300 IC50=7μM and PCAF IC50=5μM) both in vitro and in vivo. It potentiates TRAIL-induced apoptosis of cancer cells. Garcinol, independent of the cell type, induces both of the TRAIL receptors, death receptor 4 (DR4) and DR5. Garcinol neither induces the receptors of normal cells nor sensitizes them to TRAIL.
    Pureté
    >98 %
    Formula
    C38H50O6
    Solubility
    Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml).
  • Restrictions
    For Research Use only
  • Format
    Powder
    Stock
    -20 °C
  • Sujet
    Epigenetics,Posttranslational modification,Acetyltransferase,Cell death,Stem cells,Apoptosis inducer,Chromatin
    Poids moléculaire
    602.80
    Numéro CAS
    78824-30-3
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