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Mocetinostat

Inh 726169-73-9 N-(2-Aminophenyl)-4-[(4-pyridin-3-ylpyrimidin-2-ylamino)methyl]benzamide
N° du produit ABIN7233269
  • Application
    Inhibition (Inh)
    Fonction
    Class I HDAC inhibitor
    Attributs du produit
    Class I, isoform-selective HDAC inhibitor, IC50s=0.15, 0.29, 1.66 and 0.59 μM for HDAC1, 2, 3 and 11 respectively. Induces hyperacetylation of histones, induces expression of the tumor suppressor p21WAF1 and inhibits proliferation of human cancer cells. Displays antifibrotic effects in ischemic heart failure. Attenuates the development of hypersensitivity in models of neuropathic pain. Active in vivo.
    Pureté
    >98 %
    Chemical Name
    N-(2-Aminophenyl)-4-[(4-pyridin-3-ylpyrimidin-2-ylamino)methyl]benzamide
    Formula
    C23H20N6O
    Solubility
    Soluble in DMSO (up to 25 mg/ml)
  • Restrictions
    For Research Use only
  • Format
    Powder
    Stock
    RT
  • Sujet
    MGCD0103,Epigenetics,Posttranslational modification,Protein deacetylase,Neuroscience,Pain,Heart disease,Proliferation,Ischemia,Chromatin
    Poids moléculaire
    396.44
    Numéro CAS
    726169-73-9
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