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Nicotinamide

Name: Nicotinamide
Brand: antibodies-online
SKU: ABIN7233271
Price: 75.38 EUR
Availability: InStock

Inh 98-92-0 Pyridine-3-carboxylic acid amide

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N° du produit ABIN7233271

Fiche de données

Application

Inhibition (Inh)

Fonction

SIRT1 inhibitor, essential nutrient

Attributs du produit

Essential nutrient (amide form of Vitamin B3) that is incorporated into cofactors NADH/NAD+, important for ATP production and other key metabolic functions. Transiently inhibits SIRT1/SIRT3 through feedback inhibition (IC50 ~ 50 μM), but is quickly converted to NAD+ in cells. Also inhibits certain kinases (e.g. ROCK and CK1), making it a regulator of hPSC pluripotency, survival, and differentiation. Inhibits differentiation and enhances functionality of hematopoietic stem/progenitor cells (HSPCs).

Pureté

>99 %

Chemical Name

Pyridine-3-carboxylic acid amide

Formula

C6H6N2O

Solubility

Soluble in DMSO (up to 50 mg/ml) or in Water (up to 50 mg/ml)
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Restrictions

For Research Use only
Format

Powder

Stock

RT
Sujet

Nicotinic acid amide, Niacinamide, Vitamin B3, NAM,Epigenetics,DNA damage,Protein deacetylase,Kinase,Stem cells,Cancer,NAD, NADP pathways,Posttranslational modification

Poids moléculaire

122.1

Numéro CAS

98-92-0