IRAK4 Produits
(Interleukin-1 Receptor-Associated Kinase 4 (IRAK4))
Catégories
This gene encodes a kinase that activates NF-kappaB in both the Toll-like receptor (TLR) and T-cell receptor (TCR) signaling pathways. The protein is essential for most innate immune responses. Mutations in this gene result in IRAK4 deficiency and recurrent invasive pneumococcal disease. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011].
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Catégories IRAK4 en vedette
IRAK4 Anticorps
High quality antibodies with extensive validation data.
IRAK4 Kits ELISA
Reliable ELISA kits for a wide range of species.
IRAK4 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
IRAK4 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC, FACS
Validations
- (2)
- (6)
N° du produit
ABIN969218
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC (p), IHC (fro), ICC
Validations
- (6)
N° du produit
ABIN7433738
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC, IF
Validations
- (7)
N° du produit
ABIN6142522
Quantité
100 μL
Fiche technique
Fiche technique
IRAK4 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6975850
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6957197
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN1570807
Quantité
96 tests
Fiche technique
Fiche technique
IRAK4 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (2)
N° du produit
ABIN1308067
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN7123629
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1308069
Quantité
10 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits IRAK4
: "The anti-inflammatory effect and potential mechanism of cardamonin in DSS-induced colitis." dans: American journal of physiology. Gastrointestinal and liver physiology, Vol. 309, Issue 7, pp. G517-27, (2015) (PubMed).: "An unconventional role for miRNA: let-7 activates Toll-like receptor 7 and causes neurodegeneration. ..." dans: Nature neuroscience, Vol. 15, Issue 6, pp. 827-35, (2012) (PubMed).
: "Augmentation of therapeutic responses in melanoma by inhibition of IRAK-1,-4." dans: Cancer research, Vol. 72, Issue 23, pp. 6209-16, (2012) (PubMed).
: "IRAK1 and IRAK4 promote phosphorylation, ubiquitination, and degradation of MyD88 adaptor-like (Mal)." dans: The Journal of biological chemistry, Vol. 285, Issue 24, pp. 18276-82, (2010) (PubMed).
: "HIV induces both a down-regulation of IRAK-4 that impairs TLR signalling and an up-regulation of the antibiotic peptide dermcidin in monocytic cells." dans: Scandinavian journal of immunology, Vol. 70, Issue 3, pp. 264-76, (2009) (PubMed).
: "Protein kinase D1 is essential for MyD88-dependent TLR signaling pathway." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 182, Issue 10, pp. 6316-27, (2009) (PubMed).
: "IRAK-4--a shared NF-kappaB activator in innate and acquired immunity." dans: Trends in immunology, Vol. 27, Issue 12, pp. 566-72, (2006) (PubMed).
: "The role of interleukin 1 receptor-associated kinase-4 (IRAK-4) kinase activity in IRAK-4-mediated signaling." dans: The Journal of biological chemistry, Vol. 279, Issue 39, pp. 40653-8, (2004) (PubMed).
: "AATF protects neural cells against oxidative damage induced by amyloid beta-peptide." dans: Neurobiology of disease, Vol. 16, Issue 1, pp. 150-7, (2004) (PubMed).
: "Prolonged Toll-like receptor stimulation leads to down-regulation of IRAK-4 protein." dans: Journal of leukocyte biology, Vol. 76, Issue 4, pp. 904-8, (2004) (PubMed).
Synonymes et noms alternatifs relatifs à IRAK4
interleukin 1 receptor associated kinase 4 (IRAK4), interleukin 1 receptor associated kinase 4 (irak4), interleukin-1 receptor-associated kinase 4 (irak4), interleukin-1 receptor-associated kinase 4 (Irak4), 8430405M07Rik, 9330209D03Rik, ipd1, IPD1, irak-4, IRAK-4, IRAK4, irak4, ny-ran-64, ny-ren-64, NY-REN-64, ren64, REN64, zgc:55553Protein level used designations for IRAK4
- interleukin-1 receptor-associated kinase 4
- interleukin-1 receptor-associated kinase 4-like
- Interleukin-1 receptor-associated kinase 4
- renal carcinoma antigen NY-REN-64
- NY-REN-64 antigen
- interleukin-1 receptor associated kinase 4
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