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IRF4 Produits

(Interferon Regulatory Factor 4 (IRF4))
The protein encoded by this gene belongs to the IRF (interferon regulatory factor) family of transcription factors, characterized by an unique tryptophan pentad repeat DNA-binding domain. The IRFs are important in the regulation of interferons in response to infection by virus, and in the regulation of interferon-inducible genes. This family member is lymphocyte specific and negatively regulates Toll-like-receptor (TLR) signaling that is central to the activation of innate and adaptive immune systems. A chromosomal translocation involving this gene and the IgH locus, t(6\;14)(p25\;q32), may be a cause of multiple myeloma. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2010].

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Catégories IRF4 en vedette

IRF4 Anticorps

High quality antibodies with extensive validation data.

IRF4 Kits ELISA

Reliable ELISA kits for a wide range of species.

IRF4 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

IRF4 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, ELISA, IF, RNAi
Validations
  • (5)
N° du produit ABIN561526
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, IHC (p)
Validations
  • (4)
N° du produit ABIN561524
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC, IF, ICC
Validations
  • (3)
N° du produit ABIN6262655
Quantité 100 μL
Fiche technique Fiche technique

IRF4 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6956912
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human, Mouse
Analytical Method Qualitative Cell ELISA
Validations
N° du produit ABIN5648116
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN5690899
Quantité 96 tests
Fiche technique Fiche technique

IRF4 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1308086
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1308088
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7412422
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits IRF4

Bakalar, Joffe, Schmid, Son, Podolski, Fletcher: "Size-Dependent Segregation Controls Macrophage Phagocytosis of Antibody-Opsonized Targets." dans: Cell, Vol. 174, Issue 1, pp. 131-142.e13, (2018) (PubMed).

Conery, Centore, Neiss, Keller, Joshi, Spillane, Sandy, Hatton, Pardo, Zawadzke, Bommi-Reddy, Gascoigne, Bryant, Mertz, Sims: "Bromodomain inhibition of the transcriptional coactivators CBP/EP300 as a therapeutic strategy to target the IRF4 network in multiple myeloma." dans: eLife, Vol. 5, (2016) (PubMed).

Forero, Moore, Sarkar: "Role of IRF4 in IFN-stimulated gene induction and maintenance of Kaposi sarcoma-associated herpesvirus latency in primary effusion lymphoma cells." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 191, Issue 3, pp. 1476-85, (2013) (PubMed).

Han, Kraft, Nan, Guo, Chen, Qureshi, Hankinson, Hu, Duffy, Zhao, Martin, Montgomery, Hayward, Thomas, Hoover, Chanock, Hunter: "A genome-wide association study identifies novel alleles associated with hair color and skin pigmentation." dans: PLoS genetics, Vol. 4, Issue 5, pp. e1000074, (2008) (PubMed).

Nagel, Pommerenke, Meyer, Kaufmann, MacLeod, Drexler: "NKL homeobox gene MSX1 acts like a tumor suppressor in NK-cell leukemia." dans: Oncotarget, Vol. 8, Issue 40, pp. 66815-66832 (PubMed).

Synonymes et noms alternatifs relatifs à IRF4

interferon regulatory factor 4 (IRF4), interferon regulatory factor 4 (Irf4), interferon regulatory factor 4a (irf4a), Interferon regulatory factor 4 (irf4), PWWP domain-containing protein MUM1 (LOC612320), PWWP domain-containing protein MUM1 (LOC100068881), AI385587, IRF-4, IRF4, irf4, LSIRF, MUM1, NF-EM5, si:ch73-170d1.2, Spip

Protein level used designations for IRF4

  • lymphocyte-specific interferon regulatory factor
  • multiple myeloma oncogene 1
  • NF-EM5
  • PU.1 interaction partner
  • Sfpi1/PU.1 interaction partner
  • transcriptional activator PIP
  • interferon regulatory factor 4
  • irf4
  • Interferon regulatory factor 4
  • PWWP domain-containing protein MUM1
  • melanoma associated antigen (mutated) 1
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