IRF6 Produits
(Interferon Regulatory Factor 6 (IRF6))
Catégories
This gene encodes a member of the interferon regulatory transcription factor (IRF) family. Family members share a highly-conserved N-terminal helix-turn-helix DNA-binding domain and a less conserved C-terminal protein-binding domain. The encoded protein may be a transcriptional activator. Mutations in this gene can cause van der Woude syndrome and popliteal pterygium syndrome. Mutations in this gene are also associated with non-syndromic orofacial cleft type 6. Alternate splicing results in multiple transcript variants.[provided by RefSeq, May 2011].
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Catégories IRF6 en vedette
IRF6 Anticorps
High quality antibodies with extensive validation data.
IRF6 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
IRF6 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Dog, Human, Rat
Application
WB, IHC, IF, FACS, IHC (p)
Validations
- (14)
N° du produit
ABIN1498901
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IF, IP
Validations
- (5)
N° du produit
ABIN7101507
Quantité
20 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC, ELISA
Validations
- (4)
N° du produit
ABIN184730
Quantité
100 μg
Fiche technique
Fiche technique
IRF6 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6967757
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN6205230
Quantité
96 tests
Fiche technique
Fiche technique
IRF6 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1308096
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1308094
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7413994
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits IRF6
: "IRF6 Regulates Alternative Activation by Suppressing PPARγ in Male Murine Macrophages." dans: Endocrinology, Vol. 158, Issue 9, pp. 2837-2847, (2017) (PubMed).: "TGFβ3 regulates periderm removal through ΔNp63 in the developing palate." dans: Journal of cellular physiology, Vol. 230, Issue 6, pp. 1212-25, (2015) (PubMed).
: "Interferon regulatory factor 6 differentially regulates Toll-like receptor 2-dependent chemokine gene expression in epithelial cells." dans: The Journal of biological chemistry, Vol. 289, Issue 28, pp. 19758-68, (2014) (PubMed).
: "Smad4-Irf6 genetic interaction and TGF?-mediated IRF6 signaling cascade are crucial for palatal fusion in mice." dans: Development (Cambridge, England), Vol. 140, Issue 6, pp. 1220-30, (2013) (PubMed).
: "Developmental factor IRF6 exhibits tumor suppressor activity in squamous cell carcinomas." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 108, Issue 33, pp. 13710-5, (2011) (PubMed).
: "A regulatory feedback loop involving p63 and IRF6 links the pathogenesis of 2 genetically different human ectodermal dysplasias." dans: The Journal of clinical investigation, Vol. 120, Issue 5, pp. 1570-7, (2010) (PubMed).
: "Interferon regulatory factor 6 promotes cell cycle arrest and is regulated by the proteasome in a cell cycle-dependent manner." dans: Molecular and cellular biology, Vol. 28, Issue 7, pp. 2235-43, (2008) (PubMed).
: "Interferon regulatory factor 6 (IRF6) is associated with oral-facial cleft in individuals that originate in South America." dans: American journal of medical genetics. Part A, Vol. 143A, Issue 17, pp. 2075-8, (2007) (PubMed).
: "Suggestive linkage to a neighboring region of IRF6 in a cleft lip and palate multiplex family." dans: American journal of medical genetics. Part A, Vol. 143A, Issue 22, pp. 2716-21, (2007) (PubMed).
: "Mutations in IRF6 cause Van der Woude and popliteal pterygium syndromes. ..." dans: Nature genetics, Vol. 32, Issue 2, pp. 285-9, (2002) (PubMed).
Synonymes et noms alternatifs relatifs à IRF6
interferon regulatory factor 6 (IRF6), interferon regulatory factor 6 (irf6), interferon regulatory factor 6 S homeolog (irf6.S), interferon regulatory factor 6 (Irf6), AI876454, DKFZp469E012, E230028I05Rik, IRF6, lps, LPS, mirf6, ofc6, OFC6, pit, PIT, pps, PPS, PPS1, vws, VWS, VWS1, xIRF-6, zgc:63500Protein level used designations for IRF6
- interferon regulatory factor 6
- interferon regulatory factor 6-like
- IRF-6
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