ISCU Produits
(Iron-sulfur cluster assembly enzyme ISCU, mitochondrial (ISCU))
Catégories
Iron-sulfur (Fe-S) clusters are necessary for several mitochondrial enzymes and other subcellular compartment proteins. They contain sulfur and iron, and are created via several steps that include cysteine desulfurases, iron donors, chaperones, and scaffold proteins. This gene encodes the two isomeric forms, ISCU1 and ISCU2, of the Fe-S cluster scaffold protein. Mutations in this gene have been found in patients with myopathy with severe exercise intolerance and myoglobinuria. [provided by RefSeq, Jul 2008].
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Catégories ISCU en vedette
ISCU Anticorps
High quality antibodies with extensive validation data.
ISCU Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
ISCU recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, ELISA, IF
Validations
- (1)
- (4)
N° du produit
ABIN565100
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human, Mouse
Application
WB
Validations
- (5)
- (2)
N° du produit
ABIN1881467
Quantité
400 μL
Fiche technique
Fiche technique
Reactivity
Human, Mouse, Rat
Application
WB, IHC, IF, ICC
Validations
- (3)
N° du produit
ABIN6262671
Quantité
100 μL
Fiche technique
Fiche technique
ISCU recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN6229179
Quantité
96 tests
Fiche technique
Fiche technique
ISCU recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1308129
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN7288777
Quantité
200 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
N° du produit
ABIN2727308
Quantité
20 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits ISCU
: "Metabolic adaptation to chronic hypoxia in cardiac mitochondria." dans: Basic research in cardiology, Vol. 107, Issue 3, pp. 268, (2012) (PubMed).: "Dact1 is a postsynaptic protein required for dendrite, spine, and excitatory synapse development in the mouse forebrain." dans: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 30, Issue 12, pp. 4362-8, (2010) (PubMed).
: "MicroRNA-210 controls mitochondrial metabolism during hypoxia by repressing the iron-sulfur cluster assembly proteins ISCU1/2." dans: Cell metabolism, Vol. 10, Issue 4, pp. 273-84, (2009) (PubMed).
: "Clinical manifestation and a new ISCU mutation in iron-sulphur cluster deficiency myopathy." dans: Brain : a journal of neurology, Vol. 132, Issue Pt 8, pp. 2170-9, (2009) (PubMed).
: "Mapping iron binding sites on human frataxin: implications for cluster assembly on the ISU Fe-S cluster scaffold protein." dans: Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry, Vol. 13, Issue 5, pp. 825-36, (2008) (PubMed).
: "Splice mutation in the iron-sulfur cluster scaffold protein ISCU causes myopathy with exercise intolerance." dans: American journal of human genetics, Vol. 82, Issue 3, pp. 652-60, (2008) (PubMed).
Synonymes et noms alternatifs relatifs à ISCU
iron-sulfur cluster assembly enzyme ISCU, mitochondrial (LOC409130), iron-sulfur cluster assembly enzyme (ISCU), iron-sulfur cluster assembly enzyme a (iscua), iron-sulfur cluster assembly enzyme (Iscu), 2310020H20Rik, AA407971, HML, hnifU, ISU2, NIFU, Nifu, nifun, NIFUN, Nifun, RGD1309562, si:ch211-191d15.3, zC191D15.3Protein level used designations for ISCU
- iron-sulfur cluster assembly enzyme ISCU, mitochondrial
- iron-sulfur cluster scaffold homolog (E. coli)
- iron-sulfur cluster assembly enzyme
- IscU iron-sulfur cluster scaffold homolog (E. coli)
- NifU-like N-terminal domain containing
- zC191D15.3 (novel protein with leucine-rich repeat domains)
- IscU iron-sulfur cluster scaffold homolog
- iron-sulfur cluster scaffold homolog
- nifU-like N-terminal domain-containing protein
- nifU-like protein
- ISCU2
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