ITGAL Produits
(Integrin alpha-L (ITGAL))
Catégories
ITGAL encodes the integrin alpha L chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form the integrin lymphocyte function-associated antigen-1 (LFA-1), which is expressed on all leukocytes. LFA-1 plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAMs 1-3 (intercellular adhesion molecules 1 through 3), and also functions in lymphocyte costimulatory signaling. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
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Catégories ITGAL en vedette
ITGAL Anticorps
High quality antibodies with extensive validation data.
ITGAL Kits ELISA
Reliable ELISA kits for a wide range of species.
ITGAL Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
ITGAL recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
FACS, WB, IHC, ELISA
Validations
- (7)
N° du produit
ABIN7193238
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC, IF
Validations
- (7)
N° du produit
ABIN3015542
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
FACS, IP, IHC
Validations
- (1)
- (4)
N° du produit
ABIN375486
Quantité
500 μg
Fiche technique
Fiche technique
ITGAL recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6967693
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Cow
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6967694
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6960720
Quantité
96 tests
Fiche technique
Fiche technique
ITGAL recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN7123469
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
- (1)
N° du produit
ABIN2713386
Quantité
20 μg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7413577
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits ITGAL
: "Severe COVID-19 patients have impaired plasmacytoid dendritic cell-mediated control of SARS-CoV-2." dans: Nature communications, Vol. 14, Issue 1, pp. 694, (2023) (PubMed).: "T cell stiffness is enhanced upon formation of immunological synapse." dans: eLife, Vol. 10, (2021) (PubMed).
: "The Extracellular Domain of the β2 Integrin β Subunit (CD18) Is Sufficient for Escherichia coli Hemolysin and Aggregatibacter actinomycetemcomitans Leukotoxin Cytotoxic Activity." dans: mBio, Vol. 10, Issue 4, (2019) (PubMed).
: "Mutually Exclusive Roles of SHARPIN in Integrin Inactivation and NF-κB Signaling." dans: PLoS ONE, Vol. 10, Issue 11, pp. e0143423, (2015) (PubMed).
: "Expressions of CD11a, CD11b, and CD11c integrin proteins in rats with myocardial hypertrophy." dans: Iranian journal of basic medical sciences, Vol. 17, Issue 11, pp. 874-8, (2015) (PubMed).
: "Endogenous tumor-reactive CD8(+) T cells are differentiated effector cells expressing high levels of CD11a and PD-1 but are unable to control tumor growth." dans: Oncoimmunology, Vol. 2, Issue 6, pp. e23972, (2013) (PubMed).
: "LFA-1 and ICAM-1 expression induced during melanoma-endothelial cell co-culture favors the transendothelial migration of melanoma cell lines in vitro." dans: BMC cancer, Vol. 12, pp. 455, (2012) (PubMed).
: "Inhibition of human Vγ9Vδ2 T-cell antitumoral activity through HLA-G: implications for immunotherapy of cancer." dans: Cellular and molecular life sciences : CMLS, (2011) (PubMed).
: "T-lymphocyte-induced, Fas-mediated apoptosis is associated with early keratinocyte differentiation." dans: Experimental dermatology, Vol. 19, Issue 4, pp. 372-80, (2010) (PubMed).
: "Neuroprotection in a rabbit model of intraventricular haemorrhage by cyclooxygenase-2, prostanoid receptor-1 or tumour necrosis factor-alpha inhibition." dans: Brain : a journal of neurology, Vol. 133, Issue Pt 8, pp. 2264-80, (2010) (PubMed).
Synonymes et noms alternatifs relatifs à ITGAL
integrin subunit alpha L (ITGAL), integrin alpha L (Itgal), (p180), CD11A, Cd11a, CD11a, ITGAL, LFA-1, LFA-1A, LFA1A, Ly-15, Ly-21Protein level used designations for ITGAL
- CD11 antigen-like family member A
- LFA-1 alpha
- LFA-1A
- antigen CD11A (p180), lymphocyte function-associated antigen 1, alpha polypeptide
- integrin alpha-L
- integrin gene promoter
- leukocyte adhesion glycoprotein LFA-1 alpha chain
- leukocyte function-associated molecule 1 alpha chain
- lymphocyte function-associated antigen 1
- alpha L integrin
- lymphocyte antigen 15
- lymphocyte function associated antigen 1, alpha polypeptide
- integrin LFA1
- lymphocyte function-associated antigen 1, alpha polypeptide
- antigen CD11A
- lymphocyte function-associated antigen 1, alpha
- integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
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