ITPR1 Produits
(Inositol 1,4,5-Trisphosphate Receptor, Type 1 (ITPR1))
Catégories
This gene encodes an intracellular receptor for inositol 1,4,5-trisphosphate. Upon stimulation by inositol 1,4,5-trisphosphate, this receptor mediates calcium release from the endoplasmic reticulum. Mutations in this gene cause spinocerebellar ataxia type 15, a disease associated with an heterogeneous group of cerebellar disorders. Multiple transcript variants have been identified for this gene. [provided by RefSeq, Nov 2009].
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Catégories ITPR1 en vedette
ITPR1 Anticorps
High quality antibodies with extensive validation data.
ITPR1 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
ITPR1 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human, Mouse, Rat
Application
WB, IHC (p)
Validations
- (1)
- (6)
N° du produit
ABIN3043862
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
IHC, WB, IF
Validations
- (5)
N° du produit
ABIN7101690
Quantité
20 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
ELISA, IHC, IF
Validations
- (3)
N° du produit
ABIN7156293
Quantité
100 μg
Fiche technique
Fiche technique
ITPR1 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
- (1)
N° du produit
ABIN1308255
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7422271
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits ITPR1
: "Inositol 1,4,5-triphosphate receptor is selectively expressed in cerebellum but not cerebellum-like structures of the elasmobranch fish, Leucoraja erinacea." dans: Heliyon, Vol. 5, Issue 1, pp. e01176, (2019) (PubMed).: "BAP1 regulates IP3R3-mediated Ca(2+) flux to mitochondria suppressing cell transformation. ..." dans: Nature, Vol. 546, Issue 7659, pp. 549-553, (2017) (PubMed).
: "Absence of the ER Cation Channel TMEM38B/TRIC-B Disrupts Intracellular Calcium Homeostasis and Dysregulates Collagen Synthesis in Recessive Osteogenesis Imperfecta." dans: PLoS genetics, Vol. 12, Issue 7, pp. e1006156, (2016) (PubMed).
: "Association of the EF-hand and PH domains of the guanine nucleotide exchange factor SLAT with IP₃ receptor 1 promotes Ca²⁺ signaling in T cells." dans: Science signaling, Vol. 7, Issue 345, pp. ra93, (2014) (PubMed).
: "Quantitative proteomic profiling reveals novel region-specific markers in the adult mouse brain." dans: Proteomics, Vol. 14, Issue 2-3, pp. 241-61, (2014) (PubMed).
: "Divergent signaling mechanisms for venous versus arterial contraction as revealed by endothelin-1." dans: Journal of vascular surgery, (2014) (PubMed).
: "Abolished InsP3R2 function inhibits sweat secretion in both humans and mice." dans: The Journal of clinical investigation, Vol. 124, Issue 11, pp. 4773-80, (2014) (PubMed).
: "Microdomains of muscarinic acetylcholine and Ins(1,4,5)P? receptors create 'Ins(1,4,5)P? junctions' and sites of Ca²+ wave initiation in smooth muscle." dans: Journal of cell science, Vol. 125, Issue Pt 22, pp. 5315-28, (2013) (PubMed).
: "Fragmented inositol 1,4,5-trisphosphate receptors retain tetrameric architecture and form functional Ca2+ release channels." dans: The Journal of biological chemistry, Vol. 288, Issue 16, pp. 11122-34, (2013) (PubMed).
: "Proteomic analysis of primary cultured rat cortical neurons in chemical ischemia." dans: Neurochemical research, Vol. 38, Issue 8, pp. 1648-60, (2013) (PubMed).
Synonymes et noms alternatifs relatifs à ITPR1
inositol 1,4,5-trisphosphate receptor type 1 (ITPR1), inositol 1,4,5-trisphosphate receptor 1 (Itpr1), inositol 1,4,5-trisphosphate receptor, type 1 (Itpr1), D6Pas2, ENSMUSG00000072853, Gm10429, I145TR, InsP3R, InsP3R1, INSP3R1, Ip3r, IP3R, IP3R1, Itpr-1, opt, P400, Pcp-1, Pcp1, SCA15, SCA16, SCA29Protein level used designations for ITPR1
- inositol 1,4,5-triphosphate receptor, type 1
- type I inositol triphosphate receptor
- IP3 receptor
- IP3R 1
- InsP3R type I
- InsP>3
- Purkinje cell protein 1
- inositol 1,4,5-triphosphate receptor 1
- inositol 1,4,5-trisphosphate receptor type 1
- inositol 1,4,5-trisphosphate-binding protein P400
- insP3R1
- opisthotonus
- protein PCD-6
- type 1 InsP3 receptor
- type 1 inositol 1,4,5-trisphosphate receptor
- IP-3-R
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