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JAK2 Produits

(Janus Kinase 2 (JAK2))
This gene product is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. It has been found to be constituitively associated with the prolactin receptor and is required for responses to gamma interferon. Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis. [provided by RefSeq, Jul 2008].

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Catégories JAK2 en vedette

JAK2 Anticorps

High quality antibodies with extensive validation data.

JAK2 Kits ELISA

Reliable ELISA kits for a wide range of species.

JAK2 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

JAK2 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Rat
Application WB, IHC, IP, ICC
Validations
  • (7)
N° du produit ABIN7438352
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human, Mouse, Rabbit, Rat, Zebrafish (Danio rerio)
Application WB, ELISA, FACS, IHC (p), ICC, IF (cc), IF (p), IHC (fro)
Validations
  • (1)
  • (5)
N° du produit ABIN740955
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC, ELISA, FACS, ICC
Validations
  • (6)
N° du produit ABIN5542629
Quantité 100 μL
Fiche technique Fiche technique

JAK2 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (2)
  • (1)
N° du produit ABIN6957232
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6968076
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN4993543
Quantité 96 tests
Fiche technique Fiche technique

JAK2 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Insect Cells
Validations
  • (1)
N° du produit ABIN5508975
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN7123645
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN2130190
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits JAK2

Wang, Tang, Xiao, Lee, Cheng, Niu, Oguz, Feng, Lee, Li, Yang, Chen, Lan, Wu, Yu: "Stromal induction of BRD4 phosphorylation Results in Chromatin Remodeling and BET inhibitor Resistance in Colorectal Cancer." dans: Nature communications, Vol. 12, Issue 1, pp. 4441, (2021) (PubMed).

Ma, Chen, Chen, Wei, Xu, Yang, Wang, Meng, Ren, Xu: "Erythropoietin Rescues Memory Impairment in a Rat Model of Chronic Cerebral Hypoperfusion via the EPO-R/JAK2/STAT5/PI3K/Akt/GSK-3β Pathway." dans: Molecular neurobiology, Vol. 55, Issue 4, pp. 3290-3299, (2019) (PubMed).

Lan, Su, Liu, Deng, Wang, Chen, Jules, Masau, Li, Wei: "Melatonin protects circulatory death heart from ischemia/reperfusion injury via the JAK2/STAT3 signalling pathway." dans: Life sciences, Vol. 228, pp. 35-46, (2019) (PubMed).

Deng, Bu, Mo, Lv, Song, Xiao, Dan, Yang: "Huang Gan Formula Eliminates the Oxidative Stress Effects of Advanced Oxidation Protein Products on the Divergent Regulation of the Expression of AGEs Receptors via the JAK2/STAT3 Pathway." dans: Evidence-based complementary and alternative medicine : eCAM, Vol. 2017, pp. 4520916, (2018) (PubMed).

Chen, Zhou, Liu, Huang, Liu, Kang, Chen, Guo, Zhu, Sun: "Combination of gemcitabine and erlotinib inhibits recurrent pancreatic cancer growth in mice via the JAK-STAT pathway." dans: Oncology reports, Vol. 39, Issue 3, pp. 1081-1089, (2018) (PubMed).

Wu, Xu, Xu, Zheng, Chen, Jiao: "Study on the mechanism of JAK2/STAT3 signaling pathway-mediated inflammatory reaction after cerebral ischemia." dans: Molecular medicine reports, Vol. 17, Issue 4, pp. 5007-5012, (2018) (PubMed).

Liu, Li, Liang, Li, Jiang, Chu, Yang: "Hydrogen sulfide attenuates myocardial fibrosis in diabetic rats through the JAK/STAT signaling pathway." dans: International journal of molecular medicine, Vol. 41, Issue 4, pp. 1867-1876, (2018) (PubMed).

Li, Ma, Jiang, Bai, Yan, Liu, Pan, Liu, Chen: "Xiaoyaosan exerts anxiolytic-like effects by down-regulating the TNF-α/JAK2-STAT3 pathway in the rat hippocampus." dans: Scientific reports, Vol. 7, Issue 1, pp. 353, (2017) (PubMed).

Liao, Hu, Guo, Zhang, Xu, Jiang: "Promoting effects of IL‑23 on myocardial ischemia and reperfusion are associated with increased expression of IL‑17A and upregulation of the JAK2‑STAT3 signaling pathway." dans: Molecular medicine reports, Vol. 16, Issue 6, pp. 9309-9316, (2017) (PubMed).

Feng, Chen, Wang, Cheng, Zou, Zhong, Xu: "Roflumilast reverses polymicrobial sepsis-induced liver damage by inhibiting inflammation in mice." dans: Laboratory investigation; a journal of technical methods and pathology, Vol. 97, Issue 9, pp. 1008-1019, (2017) (PubMed).

Synonymes et noms alternatifs relatifs à JAK2

Janus kinase 2b (jak2b), Janus kinase 2 (JAK2), Janus kinase 2 (Jak2), AI504024, C81284, Fd17, JAK-2, jak2, JAK2bCA, JTK10, THCYT3

Protein level used designations for JAK2

  • Jak2b kinase
  • PTK JAK2b
  • protein tyrosine kinase JAK2b
  • tyrosine-protein kinase JAK2
  • JAK-2
  • Janus kinase 2 (a protein tyrosine kinase)
  • tyrosine kinase
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