JAK3 Produits
(Janus Kinase 3 (JAK3))
Catégories
The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease). [provided by RefSeq, Jul 2008].
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Catégories JAK3 en vedette
JAK3 Anticorps
High quality antibodies with extensive validation data.
JAK3 Kits ELISA
Reliable ELISA kits for a wide range of species.
JAK3 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
JAK3 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (7)
N° du produit
ABIN7439474
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, FACS, ICC
Validations
- (1)
- (4)
N° du produit
ABIN969224
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human, Mouse
Application
WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro)
Validations
- (1)
- (2)
N° du produit
ABIN681013
Quantité
100 μL
Fiche technique
Fiche technique
JAK3 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6968078
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6968077
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6957233
Quantité
96 tests
Fiche technique
Fiche technique
JAK3 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1308278
Quantité
25 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Insect Cells
Validations
N° du produit
ABIN5508976
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Rat
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7398455
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits JAK3
: "Combination of gemcitabine and erlotinib inhibits recurrent pancreatic cancer growth in mice via the JAK-STAT pathway." dans: Oncology reports, Vol. 39, Issue 3, pp. 1081-1089, (2018) (PubMed).: "Jak3 is involved in CCR7-dependent migration and invasion in metastatic squamous cell carcinoma of the head and neck." dans: Oncology letters, Vol. 13, Issue 5, pp. 3191-3197, (2017) (PubMed).
: "Direct regulation of IL-2 by curcumin." dans: Biochemical and biophysical research communications, Vol. 495, Issue 1, pp. 300-305, (2017) (PubMed).
: "JAK3 as an Emerging Target for Topical Treatment of Inflammatory Skin Diseases." dans: PloS one, Vol. 11, Issue 10, pp. e0164080, (2017) (PubMed).
: "Novel compound heterozygous mutations in a Japanese girl with Janus kinase 3 deficiency." dans: Pediatrics international : official journal of the Japan Pediatric Society, Vol. 58, Issue 10, pp. 1076-1080, (2016) (PubMed).
: "MSX3 Switches Microglia Polarization and Protects from Inflammation-Induced Demyelination." dans: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 35, Issue 16, pp. 6350-65, (2015) (PubMed).
: "Inhibition of STAT3 activation by KT-18618 via the disruption of the interaction between JAK3 and STAT3." dans: Biochemical pharmacology, Vol. 89, Issue 1, pp. 62-73, (2014) (PubMed).
: "Jak3 expression and genomic sequence in pediatric acute lymphoblastic leukemia." dans: Leukemia & lymphoma, Vol. 43, Issue 12, pp. 2355-62, (2003) (PubMed).
: "MAPKs: new JNK expands the group." dans: Trends in biochemical sciences, Vol. 19, Issue 11, pp. 470-3, (1995) (PubMed).
Synonymes et noms alternatifs relatifs à JAK3
Janus kinase 3 (JAK3), Janus kinase 3 (Jak3), fae, JAK, JAK-3, JAK3_HUMAN, JAKL, L-JAK, LJAK, RATJAK3, wilProtein level used designations for JAK3
- Janus kinase 3 (a protein tyrosine kinase, leukocyte)
- leukocyte Janus kinase
- tyrosine-protein kinase JAK3
- JAK-3
- Janus kinase 3 protein-tyrosine kinase
- Janus kinase 3, protein-tyrosine kinase
- Janus tyrosine kinase
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