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JMJD2D Produits

(Lysine (K)-Specific Demethylase 4D (KDM4D))

Catégories

Histone demethylase that specifically demethylates 'Lys- 9' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27', H3 'Lys-36' nor H4 'Lys-20'. Demethylates both di- and trimethylated H3 'Lys- 9' residue, while it has no activity on monomethylated residues. Demethylation of Lys residue generates formaldehyde and succinate (By similarity).

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Catégories JMJD2D en vedette

JMJD2D Anticorps

High quality antibodies with extensive validation data.

JMJD2D Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

JMJD2D recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Mouse, Rat
Application ELISA, WB, IHC
Validations
  • (3)
N° du produit ABIN7002265
Quantité 20 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC, IHC (p)
Validations
  • (3)
N° du produit ABIN6736292
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application ELISA, IHC, IF
Validations
  • (2)
N° du produit ABIN7158704
Quantité 100 μg
Fiche technique Fiche technique

JMJD2D recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Baculovirus
Validations
  • (3)
N° du produit ABIN2669707
Quantité 20 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1308301
Quantité 25 μg
Fiche technique Fiche technique
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
N° du produit ABIN3082371
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits JMJD2D

Duan, Perez, Chastain, Mathew, Bijukumar, Maki: "JMJD2 promotes acquired cisplatin resistance in non-small cell lung carcinoma cells." dans: Oncogene, Vol. 38, Issue 28, pp. 5643-5657, (2019) (PubMed).

Kim, Fuchs, Schwartz, Abdelhamid, Etter, Berry, Li, Ihnat, Li, Janknecht: "Pro-growth role of the JMJD2C histone demethylase in HCT-116 colon cancer cells and identification of curcuminoids as JMJD2 inhibitors." dans: American journal of translational research, Vol. 6, Issue 3, pp. 236-47, (2014) (PubMed).

Young, McDonald, Hendzel: "Kdm4b histone demethylase is a DNA damage response protein and confers a survival advantage following γ-irradiation." dans: The Journal of biological chemistry, Vol. 288, Issue 29, pp. 21376-88, (2013) (PubMed).

Kim, Oh, Shin, Janknecht: "Regulation of tumor suppressor p53 and HCT116 cell physiology by histone demethylase JMJD2D/KDM4D." dans: PLoS ONE, Vol. 7, Issue 4, pp. e34618, (2012) (PubMed).

Luo, Chang, Zhong, Pandey, Semenza: "Histone demethylase JMJD2C is a coactivator for hypoxia-inducible factor 1 that is required for breast cancer progression." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 109, Issue 49, pp. E3367-76, (2012) (PubMed).

Katoh, Katoh: "Identification and characterization of JMJD2 family genes in silico." dans: International journal of oncology, Vol. 24, Issue 6, pp. 1623-8, (2004) (PubMed).

Synonymes et noms alternatifs relatifs à JMJD2D

lysine demethylase 4D (KDM4D), lysine-specific demethylase 4D (LOC524768), lysine (K)-specific demethylase 4D (Kdm4d), lysine-specific demethylase 4D (LOC617971), lysine-specific demethylase 4D (LOC100067461), lysine demethylase 4D (Kdm4d), lysine-specific demethylase 4D (LOC698455), lysine (K)-specific demethylase 4D (KDM4D), lysine-specific demethylase 4D (LOC100514356), 4932416A15, JMJD2D, Jmjd2d, KDM4D

Protein level used designations for JMJD2D

  • jmjC domain-containing histone demethylation protein 3D
  • jumonji domain containing 2D
  • jumonji domain-containing protein 2D
  • lysine-specific demethylase 4D
  • lysine (K)-specific demethylase 4D
  • lysine-specific demethylase 4D-like
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