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JUP Produits

(Junction Plakoglobin (JUP))

Catégories

This gene encodes a major cytoplasmic protein which is the only known constituent common to submembranous plaques of both desmosomes and intermediate junctions. This protein forms distinct complexes with cadherins and desmosomal cadherins and is a member of the catenin family since it contains a distinct repeating amino acid motif called the armadillo repeat. Mutation in this gene has been associated with Naxos disease. Alternative splicing occurs in this gene\; however, not all transcripts have been fully described. [provided by RefSeq, Jul 2008].

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Catégories JUP en vedette

JUP Anticorps

High quality antibodies with extensive validation data.

JUP Kits ELISA

Reliable ELISA kits for a wide range of species.

JUP Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

JUP recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IHC, ELISA, ICC
Validations
  • (1)
  • (6)
N° du produit ABIN969225
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC, IF
Validations
  • (7)
N° du produit ABIN7101634
Quantité 20 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IF, ELISA, IHC (p)
Validations
  • (6)
N° du produit ABIN561572
Quantité 100 μg
Fiche technique Fiche technique

JUP recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
N° du produit ABIN6957240
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6968085
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Analytical Method Qualitative Cell ELISA
Validations
N° du produit ABIN1380988
Quantité 96 tests
Fiche technique Fiche technique

JUP recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
  • (1)
N° du produit ABIN1308342
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7396034
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
N° du produit ABIN2723948
Quantité 20 μg
Fiche technique Fiche technique

Dernières publications sur nos produits JUP

Seo, Sakon, Nakazawa, Nishioka, Watanabe, Matsumoto, Akasaka, Shioi, Sawada, Araki: "Haemorrhagic snake venom metalloproteases and human ADAMs cleave LRP5/6, which disrupts cell-cell adhesions in vitro and induces haemorrhage in vivo." dans: The FEBS journal, Vol. 284, Issue 11, pp. 1657-1671, (2017) (PubMed).

Ortega-Martínez, Gardeazabal, Erramuzpe, Sanchez-Diez, Cortés, García-Vázquez, Pérez-Yarza, Izu, Luís Díaz-Ramón, de la Fuente, Asumendi, Boyano: "Vitronectin and dermcidin serum levels predict the metastatic progression of AJCC I-II early-stage melanoma." dans: International journal of cancer, Vol. 139, Issue 7, pp. 1598-607, (2016) (PubMed).

Aktary, Kulak, Mackey, Jahroudi, Pasdar: "Plakoglobin interacts with the transcription factor p53 and regulates the expression of 14-3-3σ." dans: Journal of cell science, Vol. 126, Issue Pt 14, pp. 3031-42, (2013) (PubMed).

Cooksley-Decasper, Reiser, Thommen, Biedermann, Neidhart, Gawinecka, Cathomas, Franzeck, Wyss, Klingenberg, Nanni, Roschitzki, Matter, Wolint, Emmert, Husmann, Amann-Vesti, Maier, Gay, Lüscher et al.: "Antibody phage display assisted identification of junction plakoglobin as a potential biomarker for atherosclerosis. ..." dans: PLoS ONE, Vol. 7, Issue 10, pp. e47985, (2012) (PubMed).

Shair, Schnegg, Raab-Traub: "Epstein-Barr virus latent membrane protein-1 effects on junctional plakoglobin and induction of a cadherin switch." dans: Cancer research, Vol. 69, Issue 14, pp. 5734-42, (2009) (PubMed).

Akins, Greer: "Axon behavior in the olfactory nerve reflects the involvement of catenin-cadherin mediated adhesion." dans: The Journal of comparative neurology, Vol. 499, Issue 6, pp. 979-89, (2007) (PubMed).

Miravet, Piedra, Castaño, Raurell, Francí, Duñach, García de Herreros: "Tyrosine phosphorylation of plakoglobin causes contrary effects on its association with desmosomes and adherens junction components and modulates beta-catenin-mediated transcription." dans: Molecular and cellular biology, Vol. 23, Issue 20, pp. 7391-402, (2003) (PubMed).

Mary, Charrasse, Meriane, Comunale, Travo, Blangy, Gauthier-Rouvière: "Biogenesis of N-cadherin-dependent cell-cell contacts in living fibroblasts is a microtubule-dependent kinesin-driven mechanism." dans: Molecular biology of the cell, Vol. 13, Issue 1, pp. 285-301, (2002) (PubMed).

Merritt, Berika, Zhai, Kirk, Ji, Hardman, Garrod: "Suprabasal desmoglein 3 expression in the epidermis of transgenic mice results in hyperproliferation and abnormal differentiation." dans: Molecular and cellular biology, Vol. 22, Issue 16, pp. 5846-58, (2002) (PubMed).

Peng, Mandai, Nakanishi, Ikeda, Asada, Momose, Shibamoto, Yanagihara, Shiozaki, Monden, Takeichi, Takai: "Restoration of E-cadherin-based cell-cell adhesion by overexpression of nectin in HSC-39 cells, a human signet ring cell gastric cancer cell line." dans: Oncogene, Vol. 21, Issue 26, pp. 4108-19, (2002) (PubMed).

Synonymes et noms alternatifs relatifs à JUP

junction plakoglobin (JUP), junction plakoglobin (Jup), junction plakoglobin (jup), junction plakoglobin L homeolog (jup.L), junction plakoglobin (Tsp_06656), Junction plakoglobin (plak), junction plakoglobin a (jupa), junction plakoglobin S homeolog (jup.S), ARVD12, arvd12, cb80, CTNNG, ctnng, D930025P04Rik, danPG, DP3, dp3, DPIII, dpiii, fb11b06, jup, PDGB, pdgb, PG, PKGB, pkgb, plak, wu:fb11b06

Protein level used designations for JUP

  • catenin (cadherin-associated protein), gamma 80kDa
  • desmoplakin III
  • desmoplakin-3
  • gamma-catenin (plakoglobin)
  • desmoplakin 3
  • junction plakoglobin
  • Junction plakoglobin
  • junction plakoglobin-like
  • gamma-catenin
  • plakoglobin
  • gama-catenin
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