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Kallikrein 5 Produits

(Kallikrein 5 (KLK5))

Catégories

Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its expression is up-regulated by estrogens and progestins. The encoded protein is secreted and may be involved in desquamation in the epidermis. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008].

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Catégories Kallikrein 5 en vedette

Kallikrein 5 Anticorps

High quality antibodies with extensive validation data.

Kallikrein 5 Kits ELISA

Reliable ELISA kits for a wide range of species.

Kallikrein 5 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

Kallikrein 5 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Mouse
Application WB
Validations
  • (1)
  • (2)
N° du produit ABIN390305
Quantité 400 μL
Fiche technique Fiche technique
Reactivity Mouse
Application WB, IHC, IP, ICC
Validations
  • (2)
N° du produit ABIN7431812
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (2)
N° du produit ABIN7157213
Quantité 100 μg
Fiche technique Fiche technique

Kallikrein 5 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6957250
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6957251
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6976005
Quantité 96 tests
Fiche technique Fiche technique

Kallikrein 5 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (3)
N° du produit ABIN7275095
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Mouse
Source HEK-293 Cells
Validations
  • (2)
N° du produit ABIN7275097
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1308863
Quantité 10 μg
Fiche technique Fiche technique

Dernières publications sur nos produits Kallikrein 5

Ma, Hockla, Mehner, Coban, Papo, Radisky, Radisky: "PRSS3/Mesotrypsin and kallikrein-related peptidase 5 are associated with poor prognosis and contribute to tumor cell invasion and growth in lung adenocarcinoma." dans: Scientific reports, Vol. 9, Issue 1, pp. 1844, (2019) (PubMed).

Jennemann, Rabionet, Gorgas, Epstein, Dalpke, Rothermel, Bayerle, van der Hoeven, Imgrund, Kirsch, Nickel, Willecke, Riezman, Gröne, Sandhoff: "Loss of ceramide synthase 3 causes lethal skin barrier disruption." dans: Human molecular genetics, Vol. 21, Issue 3, pp. 586-608, (2012) (PubMed).

Jiang, Shi, Johnson, Liu, Stack: "Kallikrein-5 promotes cleavage of desmoglein-1 and loss of cell-cell cohesion in oral squamous cell carcinoma." dans: The Journal of biological chemistry, Vol. 286, Issue 11, pp. 9127-35, (2011) (PubMed).

Michael, Pampalakis, Mikolajczyk, Malm, Sotiropoulou, Diamandis: "Human tissue kallikrein 5 is a member of a proteolytic cascade pathway involved in seminal clot liquefaction and potentially in prostate cancer progression." dans: The Journal of biological chemistry, Vol. 281, Issue 18, pp. 12743-50, (2006) (PubMed).

Ishida-Yamamoto, Deraison, Bonnart, Bitoun, Robinson, OBrien, Wakamatsu, Ohtsubo, Takahashi, Hashimoto, Dopping-Hepenstal, McGrath, Iizuka, Richard, Hovnanian: "LEKTI is localized in lamellar granules, separated from KLK5 and KLK7, and is secreted in the extracellular spaces of the superficial stratum granulosum." dans: The Journal of investigative dermatology, Vol. 124, Issue 2, pp. 360-6, (2005) (PubMed).

Michael, Sotiropoulou, Pampalakis, Magklara, Ghosh, Wasney, Diamandis: "Biochemical and enzymatic characterization of human kallikrein 5 (hK5), a novel serine protease potentially involved in cancer progression." dans: The Journal of biological chemistry, Vol. 280, Issue 15, pp. 14628-35, (2005) (PubMed).

Planque, de Monte, Guyetant, Rollin, Desmazes, Panel, Lemarié, Courty: "KLK5 and KLK7, two members of the human tissue kallikrein family, are differentially expressed in lung cancer." dans: Biochemical and biophysical research communications, Vol. 329, Issue 4, pp. 1260-6, (2005) (PubMed).

Synonymes et noms alternatifs relatifs à Kallikrein 5

kallikrein related peptidase 5 (KLK5), kallikrein related-peptidase 5 (Klk5), kallikrein 5-like (Klk5l), 1110030O19Rik, KAL, KALA, KLK-L2, Klk1, Klk5, KLKL2, RATKALA, SCTE

Protein level used designations for Kallikrein 5

  • kallikrein 5
  • kallikrein-5
  • kallikrein-like protein 2
  • stratum corneum tryptic enzyme
  • Kallikrein 1 renal/pancreas/salivary
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