KAT2A Produits
(K(lysine) Acetyltransferase 2A (KAT2A))
Catégories
KAT2A, or GCN5, is a histone acetyltransferase (HAT) that functions primarily as a transcriptional activator. It also functions as a repressor of NF-kappa-B (see MIM 164011) by promoting ubiquitination of the NF-kappa-B subunit RELA (MIM 164014) in a HAT-independent manner (Mao et al., 2009 [PubMed 19339690]).[supplied by OMIM, Sep 2009].
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Catégories KAT2A en vedette
KAT2A Anticorps
High quality antibodies with extensive validation data.
KAT2A Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
KAT2A recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human, Mouse, Rat
Application
IHC, IF
Validations
- (6)
N° du produit
ABIN7260323
Quantité
200 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IF
Validations
- (8)
N° du produit
ABIN1679964
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, IF
Validations
- (3)
N° du produit
ABIN515990
Quantité
100 μg
Fiche technique
Fiche technique
KAT2A recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN7123656
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN667533
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1308354
Quantité
10 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits KAT2A
: "H3 ubiquitination by NEDD4 regulates H3 acetylation and tumorigenesis." dans: Nature communications, Vol. 8, pp. 14799, (2017) (PubMed).: "Upregulation of KLF4 by methylseleninic acid in human esophageal squamous cell carcinoma cells: Modification of histone H3 acetylation through HAT/HDAC interplay." dans: Molecular carcinogenesis, Vol. 54, Issue 10, pp. 1051-9, (2015) (PubMed).
: "A potent and selective Sirtuin 1 inhibitor alleviates pathology in multiple animal and cell models of Huntington's disease. ..." dans: Human molecular genetics, Vol. 23, Issue 11, pp. 2995-3007, (2014) (PubMed).
: "Acetylation of conserved lysines in the catalytic core of cyclin-dependent kinase 9 inhibits kinase activity and regulates transcription." dans: Molecular and cellular biology, Vol. 28, Issue 7, pp. 2201-12, (2008) (PubMed).
: "Glucocorticoid-stimulated preadipocyte differentiation is mediated through acetylation of C/EBPbeta by GCN5." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, Issue 8, pp. 2703-8, (2007) (PubMed).
: "An hGCN5/TRRAP histone acetyltransferase complex co-activates BRCA1 transactivation function through histone modification." dans: The Journal of biological chemistry, Vol. 281, Issue 1, pp. 20-6, (2006) (PubMed).
: "GCN5: a supervisor in all-inclusive control of vertebrate cell cycle progression through transcription regulation of various cell cycle-related genes." dans: Gene, Vol. 347, Issue 1, pp. 83-97, (2005) (PubMed).
: "The transforming acidic coiled coil proteins interact with nuclear histone acetyltransferases." dans: Oncogene, Vol. 23, Issue 14, pp. 2559-63, (2004) (PubMed).
: "Regulation of HIV-1 gene expression by histone acetylation and factor recruitment at the LTR promoter." dans: The EMBO journal, Vol. 22, Issue 24, pp. 6550-61, (2003) (PubMed).
: "UV-damaged DNA-binding protein in the TFTC complex links DNA damage recognition to nucleosome acetylation." dans: The EMBO journal, Vol. 20, Issue 12, pp. 3187-96, (2001) (PubMed).
Synonymes et noms alternatifs relatifs à KAT2A
K(lysine) acetyltransferase 2A (KAT2A), lysine acetyltransferase 2A (KAT2A), histone acetyltransferase KAT2A (LOC100176452), ras-related protein Rab-5C (LOC100597293), K(lysine) acetyltransferase 2A (Kat2a), lysine acetyltransferase 2A (Kat2a), 1110051E14Rik, AW212720, GCN5, Gcn5, GCN5L2, Gcn5l2, hGCN5, KAT2A, mmGCN5, PCAF-bProtein level used designations for KAT2A
- histone acetyltransferase KAT2A
- general control of amino acid synthesis 5-like 2
- GCN5 general control of amino-acid synthesis 5-like 2
- general control of amino acid synthesis protein 5-like 2
- K(lysine) acetyltransferase 2A
- GCN5 (general control of amino-acid synthesis, yeast, homolog)-like 2
- General control of amino acid synthesis, yeast, homolog-like 2
- STAF97
- histone acetyltransferase GCN5
- hsGCN5
- lysine acetyltransferase 2A
- GCN5 general control of amino acid synthesis-like 2
- PCAF-B/GCN5
- general control of amino acid synthesis, yeast homolog-like 2
- general control of amino acid synthesis-like 2
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