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KAT6B Produits

(K(lysine) Acetyltransferase 6B (KAT6B))

Catégories

The protein encoded by this gene is a histone acetyltransferase and component of the MOZ/MORF protein complex. In addition to its acetyltransferase activity, the encoded protein has transcriptional activation activity in its N-terminal end and transcriptional repression activity in its C-terminal end. This protein is necessary for RUNX2-dependent transcriptional activation and could be involved in brain development. Mutations have been found in patients with genitopatellar syndrome. A translocation of this gene and the CREBBP gene results in acute myeloid leukemias. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2012].

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Catégories KAT6B en vedette

KAT6B Anticorps

High quality antibodies with extensive validation data.

KAT6B recommandé Anticorps

Produit

Reactivity

Application

Validations

N° du produit

Quantité

Fiche technique

anti-KAT6B anticorps (AA 1186-1318)

Reactivity Human

Application ELISA

Validations

N° du produit ABIN7193390

Quantité 100 μL

Fiche technique Fiche technique

anti-KAT6B anticorps (C-Term)

Reactivity Human, Mouse

Application WB, ELISA, IHC

Validations

N° du produit ABIN6263496

Quantité 100 μL

Fiche technique Fiche technique

anti-KAT6B anticorps (AA 80-172)

Reactivity Human

Application WB, ELISA

Validations

N° du produit ABIN565103

Quantité 50 μL

Fiche technique Fiche technique

Dernières publications sur nos produits KAT6B

McGraw, Morin, Vigneault, Leclerc, Sirard: "Investigation of MYST4 histone acetyltransferase and its involvement in mammalian gametogenesis." dans: BMC developmental biology, Vol. 7, pp. 123, (2008) (PubMed).

Pena, Pereira-Smith: "The role of the MORF/MRG family of genes in cell growth, differentiation, DNA repair, and thereby aging." dans: Annals of the New York Academy of Sciences, Vol. 1100, pp. 299-305, (2007) (PubMed).

Olsen, Blagoev, Gnad, Macek, Kumar, Mortensen, Mann: "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks." dans: Cell, Vol. 127, Issue 3, pp. 635-48, (2006) (PubMed).

Liu, Lu, Tan, Li, Huang: "Human interleukin-5 expression is synergistically regulated by histone acetyltransferase CBP/p300 and transcription factors C/EBP, NF-AT and AP-1." dans: Cytokine, Vol. 27, Issue 4-5, pp. 93-100, (2004) (PubMed).

Utley, C�té: "The MYST family of histone acetyltransferases." dans: Current topics in microbiology and immunology, Vol. 274, pp. 203-36, (2003) (PubMed).

Synonymes et noms alternatifs relatifs à KAT6B

K(lysine) acetyltransferase 6B (kat6b), lysine acetyltransferase 6B (KAT6B), K(lysine) acetyltransferase 6B (Kat6b), AI507552, B130044K16Rik, GTPTS, id:ibd5103, mKIAA0383, MORF, Morf, MOZ2, MYST-4, MYST4, Myst4, qkf, querkopf, si:dkey-24f15.3, ZC2HC6B