K-RAS Produits
(GTPase Kras (KRAS))
Catégories
This gene, a Kirsten ras oncogene homolog from the mammalian ras gene family, encodes a protein that is a member of the small GTPase superfamily. A single amino acid substitution is responsible for an activating mutation. The transforming protein that results is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. Alternative splicing leads to variants encoding two isoforms that differ in the C-terminal region. [provided by RefSeq, Jul 2008].
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Catégories K-RAS en vedette
K-RAS Anticorps
High quality antibodies with extensive validation data.
K-RAS Kits ELISA
Reliable ELISA kits for a wide range of species.
K-RAS Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
K-RAS recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, ELISA, IF
Validations
- (5)
- (5)
N° du produit
ABIN561621
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA
Validations
- (1)
- (4)
N° du produit
ABIN561622
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IF, FACS
Validations
- (7)
N° du produit
ABIN3031120
Quantité
0.2 mL
Fiche technique
Fiche technique
K-RAS recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6962518
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6956365
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN5659809
Quantité
96 tests
Fiche technique
Fiche technique
K-RAS recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN7319807
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN7123229
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN667031
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits K-RAS
: "EPHA2 feedback activation limits the response to PDEδ inhibition in KRAS-dependent cancer cells." dans: Acta pharmacologica Sinica, Vol. 41, Issue 2, pp. 270-277, (2020) (PubMed).: "Modulation of EZH2 Expression by MEK-ERK or PI3K-AKT Signaling in Lung Cancer Is Dictated by Different KRAS Oncogene Mutations." dans: Cancer research, Vol. 76, Issue 3, pp. 675-85, (2016) (PubMed).
: "Cell surface protease activation during RAS transformation: Critical role of the plasminogen receptor, S100A10." dans: Oncotarget, Vol. 7, Issue 30, pp. 47720-47737, (2016) (PubMed).
: "Let-7a regulates mammosphere formation capacity through Ras/NF-κB and Ras/MAPK/ERK pathway in breast cancer stem cells." dans: Cell cycle (Georgetown, Tex.), Vol. 14, Issue 11, pp. 1686-97, (2015) (PubMed).
: "Evidence for aldosterone-dependent growth of renal cell carcinoma." dans: International journal of experimental pathology, Vol. 95, Issue 4, pp. 244-50, (2014) (PubMed).
: "Overexpression of DDX43 mediates MEK inhibitor resistance through RAS Upregulation in uveal melanoma cells." dans: Molecular cancer therapeutics, Vol. 13, Issue 8, pp. 2073-80, (2014) (PubMed).
: "KRAS gene amplification in colorectal cancer and impact on response to EGFR-targeted therapy. ..." dans: International journal of cancer. Journal international du cancer, Vol. 133, Issue 5, pp. 1259-65, (2013) (PubMed).
: "4-Hydroxytamoxifen induces autophagic death through K-Ras degradation." dans: Cancer research, Vol. 73, Issue 14, pp. 4395-405, (2013) (PubMed).
: "Synergistic effects of combined Wnt/KRAS inhibition in colorectal cancer cells." dans: PLoS ONE, Vol. 7, Issue 12, pp. e51449, (2012) (PubMed).
: "Analysis of k-ras nuclear expression in fibroblasts and mesangial cells." dans: PLoS ONE, Vol. 5, Issue 1, pp. e8703, (2010) (PubMed).
Synonymes et noms alternatifs relatifs à K-RAS
KRAS proto-oncogene, GTPase (KRAS), v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog (kras), KRAS proto-oncogene, GTPase (Kras), Kirsten rat sarcoma viral oncogene homolog (Kras), semicolonial-7 (smco-7), Ras family protein (PGTG_03066), GTPase KRas (Tsp_02666), GTPase KRas (Tsp_01642), GTPase KRas (rask), Kirsten rat sarcoma viral oncogene homolog S homeolog (kras.S), AI929937, C-K-RAS, c-Ki-ras, CFC2, K-ras, k-ras, K-RAS, K-RAS2A, K-RAS2B, K-RAS4A, K-RAS4B, KI-RAS, Ki-ras, kras, Kras-2, kras-a, kras-b, KRAS1, Kras2, KRAS2, NS, NS3, p21, p21B, p21ras, ras, RASK2, rask2, wu:fa04e08, wu:fc14b12, wu:fc23g10, wu:fj89d12, zgc:85725Protein level used designations for K-RAS
- GTPase KRas
- fa04e08
- fc14b12
- fc23g10
- fj89d12
- xRAS2
- K-Ras 2
- Kirsten rat sarcoma viral oncogene homologue 2 (active)
- c-K-ras
- c-K-ras2 protein
- c-Kirsten-ras proto-oncogene
- ki-Ras
- v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
- K-ras p21 protein
- PR310 c-K-ras oncogene
- c-Ki-ras
- c-Kirsten-ras protein
- cellular c-Ki-ras2 proto-oncogene
- oncogene KRAS2
- transforming protein p21
- v-Ki-ras2 Kirsten rat sarcoma 2 viral oncogene homolog
- Kirsten rat sarcoma oncogene 2, expressed
- p21 protein
- Kirsten rat sarcoma viral oncogene homolog S homeolog
- ras protein
- ras p21
- Kirsten rat sarcoma viral oncogene homolog
- Kirsten rat sarcoma viral (Kras-2) oncogene homolog
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