KCC2 Produits
(Solute Carrier Family 12 (Potassium-Chloride Transporter) Member 5 (SLC12A5))
Catégories
K-Cl cotransporters are proteins that lower intracellular chloride concentrations below the electrochemical equilibrium potential. The protein encoded by this gene is an integral membrane K-Cl cotransporter that can function in either a net efflux or influx pathway, depending on the chemical concentration gradients of potassium and chloride. The encoded protein can act as a homomultimer, or as a heteromultimer with other K-Cl cotransporters, to maintain chloride homeostasis in neurons. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Sep 2008].
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Catégories KCC2 en vedette
KCC2 Anticorps
High quality antibodies with extensive validation data.
KCC2 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
KCC2 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Rat
Application
WB, IHC, IP, IF, ICC
Validations
- (4)
N° du produit
ABIN1027708
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC (p)
Validations
- (3)
N° du produit
ABIN652057
Quantité
400 μL
Fiche technique
Fiche technique
Reactivity
Mouse, Rat
Application
IHC, IF
Validations
- (3)
N° du produit
ABIN7075650
Quantité
100 μL
Fiche technique
Fiche technique
KCC2 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN6210805
Quantité
96 tests
Fiche technique
Fiche technique
KCC2 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
N° du produit
ABIN3118086
Quantité
1 mg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
N° du produit
ABIN3136773
Quantité
1 mg
Fiche technique
Fiche technique
Dernières publications sur nos produits KCC2
: "The adipocyte hormone leptin sets the emergence of hippocampal inhibition in mice." dans: eLife, Vol. 7, (2019) (PubMed).: "Calpain-2 as a Treatment Target in Prenatal Stress-induced Epileptic Spasms in Infant Rats." dans: Experimental neurobiology, Vol. 28, Issue 4, pp. 529-536, (2019) (PubMed).
: "Ionic plasticity and pain: The loss of descending serotonergic fibers after spinal cord injury transforms how GABA affects pain." dans: Experimental neurology, Vol. 306, pp. 105-116, (2019) (PubMed).
: "Native KCC2 interactome reveals PACSIN1 as a critical regulator of synaptic inhibition." dans: eLife, Vol. 6, (2018) (PubMed).
: "Mutations in SLC12A5 in epilepsy of infancy with migrating focal seizures. ..." dans: Nature communications, Vol. 6, pp. 8038, (2015) (PubMed).
: "Neto2-null mice have impaired GABAergic inhibition and are susceptible to seizures." dans: Frontiers in cellular neuroscience, Vol. 9, pp. 368, (2015) (PubMed).
: "Down-regulation of KCC2 expression and phosphorylation in motoneurons, and increases the number of in primary afferent projections to motoneurons in mice with post-stroke spasticity." dans: PLoS ONE, Vol. 9, Issue 12, pp. e114328, (2015) (PubMed).
: "The developmental switch in GABA polarity is delayed in fragile X mice." dans: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 34, Issue 2, pp. 446-50, (2014) (PubMed).
: "Distribution of neuronal KCC2a and KCC2b isoforms in mouse CNS." dans: The Journal of comparative neurology, Vol. 522, Issue 8, pp. 1897-914, (2014) (PubMed).
: "Emergence of motor circuit activity." dans: PLoS ONE, Vol. 9, Issue 4, pp. e93836, (2014) (PubMed).
Synonymes et noms alternatifs relatifs à KCC2
solute carrier family 12 member 5 (SLC12A5), solute carrier family 12 member 5 (Slc12a5), solute carrier family 12, member 5 (Slc12a5), Kcc2, KCC2, mKIAA1176Protein level used designations for KCC2
- solute carrier family 12 (potassium/chloride transporter), member 5
- K-Cl cotransporter 2
- electroneutral potassium-chloride cotransporter 2
- furosemide-sensitive K-Cl cotransporter
- neuronal K-Cl cotransporter
- neuronal-specific K-Cl cotransporter
- rKCC2
- solute carrier family 12 member 5
- solute carrier family 12, member 5
- erythroid K-Cl cotransporter 2
- hKCC2
- mKCC2
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