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KCNJ1 Produits

(Potassium Inwardly-Rectifying Channel, Subfamily J, Member 1 (KCNJ1))

Catégories

Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. It is activated by internal ATP and probably plays an important role in potassium homeostasis. The encoded protein has a greater tendency to allow potassium to flow into a cell rather than out of a cell. Mutations in this gene have been associated with antenatal Bartter syndrome, which is characterized by salt wasting, hypokalemic alkalosis, hypercalciuria, and low blood pressure. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

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Catégories KCNJ1 en vedette

KCNJ1 Anticorps

High quality antibodies with extensive validation data.

KCNJ1 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

KCNJ1 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Mouse, Rat
Application WB, IHC
Validations
  • (3)
N° du produit ABIN7264605
Quantité 200 μL
Fiche technique Fiche technique
Reactivity Human
Application ELISA, IHC, IF
Validations
  • (2)
N° du produit ABIN7145017
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application ELISA, WB, IF
Validations
  • (2)
N° du produit ABIN7145013
Quantité 100 μg
Fiche technique Fiche technique

KCNJ1 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN6210712
Quantité 96 tests
Fiche technique Fiche technique

KCNJ1 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1308433
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1780435
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
N° du produit ABIN3113680
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits KCNJ1

Zachar, Al-Mashhadi, Dimke, Svenningsen, Jensen, Carlström: "Hydronephrosis is associated with elevated plasmin in urine in pediatric patients and rats and changes in NCC and γ-ENaC abundance in rat kidney." dans: American journal of physiology. Renal physiology, Vol. 315, Issue 3, pp. F547-F557, (2018) (PubMed).

Vidal-Petiot, Elvira-Matelot, Mutig, Soukaseum, Baudrie, Wu, Cheval, Huc, Cambillau, Bachmann, Doucet, Jeunemaitre, Hadchouel: "WNK1-related Familial Hyperkalemic Hypertension results from an increased expression of L-WNK1 specifically in the distal nephron." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, Issue 35, pp. 14366-71, (2013) (PubMed).

Bhave, Chauder, Liu, Dawson, Kadakia, Nguyen, Lewis, Meiler, Weaver, Satlin, Lindsley, Denton: "Development of a selective small-molecule inhibitor of Kir1.1, the renal outer medullary potassium channel." dans: Molecular pharmacology, Vol. 79, Issue 1, pp. 42-50, (2010) (PubMed).

Tobin, Tomaszewski, Braund, Hajat, Raleigh, Palmer, Caulfield, Burton, Samani: "Common variants in genes underlying monogenic hypertension and hypotension and blood pressure in the general population." dans: Hypertension, Vol. 51, Issue 6, pp. 1658-64, (2008) (PubMed).

Ji, Foo, ORoak, Zhao, Larson, Simon, Newton-Cheh, State, Levy, Lifton: "Rare independent mutations in renal salt handling genes contribute to blood pressure variation." dans: Nature genetics, Vol. 40, Issue 5, pp. 592-9, (2008) (PubMed).

Synonymes et noms alternatifs relatifs à KCNJ1

potassium voltage-gated channel subfamily J member 1 (KCNJ1), potassium voltage-gated channel subfamily J member 1 L homeolog (kcnj1.L), potassium voltage-gated channel subfamily J member 1 (kcnj1), potassium voltage-gated channel subfamily J member 1 (Kcnj1), potassium inwardly-rectifying channel, subfamily J, member 1 (Kcnj1), potassium inwardly-rectifying channel, subfamily J, member 1a, tandem duplicate 1 (kcnj1a.1), Kcnj, kcnj1, KIR1.1, kir1.1, Kir1.1, ROMK, ROMK1, romk1, Romk2, wu:fl37c05, zgc:63534

Protein level used designations for KCNJ1

  • ATP-regulated potassium channel ROM-K
  • ATP-sensitive inward rectifier potassium channel 1
  • inward rectifier K(+) channel Kir1.1
  • inwardly rectifying K+ channel
  • potassium channel, inwardly rectifying subfamily J member 1
  • potassium inwardly-rectifying channel, subfamily J, member 1
  • potassium inwardly-rectifying channel J1
  • ATP-sensitive inward rectifier potassium channel 1-like
  • K+ channel protein
  • KAB-1
  • Potassium inwardly-rectifying channel subfamily J
  • kir1.1
  • inwardly rectifying potassium channel ROMK-2
  • LOW QUALITY PROTEIN: ATP-sensitive inward rectifier potassium channel 1
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