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KDM4A Produits

(Lysine (K)-Specific Demethylase 4A (KDM4A))
This gene is a member of the Jumonji domain 2 (JMJD2) family and encodes a protein containing a JmjN domain, a JmjC domain, a JD2H domain, two TUDOR domains, and two PHD-type zinc fingers. This nuclear protein functions as a trimethylation-specific demethylase, converting specific trimethylated histone residues to the dimethylated form, and as a transcriptional repressor. [provided by RefSeq, Apr 2009].

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Catégories KDM4A en vedette

KDM4A Anticorps

High quality antibodies with extensive validation data.

KDM4A Kits ELISA

Reliable ELISA kits for a wide range of species.

KDM4A Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

KDM4A recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (6)
N° du produit ABIN7441397
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application ELISA, ICC, FACS
Validations
  • (5)
N° du produit ABIN5542632
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application ELISA, IHC, ICC
Validations
  • (4)
  • (3)
N° du produit ABIN969230
Quantité 100 μL
Fiche technique Fiche technique

KDM4A recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6957575
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN5656536
Quantité 96 tests
Fiche technique Fiche technique

KDM4A recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN7123808
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Human
Source Baculovirus
Validations
  • (2)
N° du produit ABIN2669705
Quantité 20 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7408756
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits KDM4A

Xu, Moresco, Chang, Mukim, Smith, Diedrich, Yates, Jones: "SHMT2 and the BRCC36/BRISC deubiquitinase regulate HIV-1 Tat K63-ubiquitylation and destruction by autophagy." dans: PLoS pathogens, Vol. 14, Issue 5, pp. e1007071, (2018) (PubMed).

Carbonneau, M Gagné, Lalonde, Germain, Motorina, Guiot, Secco, Vincent, Tumber, Hulea, Bergeman, Oppermann, Jones, Laplante, Topisirovic, Petrecca, Huot, Mallette: "The oncometabolite 2-hydroxyglutarate activates the mTOR signalling pathway." dans: Nature communications, Vol. 7, pp. 12700, (2016) (PubMed).

Gibbs-Seymour, Markiewicz, Bekker-Jensen, Mailand, Hutchison: "Lamin A/C-dependent interaction with 53BP1 promotes cellular responses to DNA damage." dans: Aging cell, Vol. 14, Issue 2, pp. 162-9, (2015) (PubMed).

Qiu, Fan, Zhu, Kwan, Chen, Chen, Ying, Zhou, Gu, Wang, Cheng, Zeng, Wan, Mok, Wong, Bao: "KDM4B and KDM4A promote endometrial cancer progression by regulating androgen receptor, c-myc, and p27kip1." dans: Oncotarget, Vol. 6, Issue 31, pp. 31702-20, (2015) (PubMed).

Satterlee, Beckel-Mitchener, McAllister, Procaccini, Rutter, Tyson, Chadwick: "Community resources and technologies developed through the NIH Roadmap Epigenomics Program." dans: Methods in molecular biology (Clifton, N.J.), Vol. 1238, pp. 27-49, (2014) (PubMed).

Das, Chai, Jung, Das, Kang, Lee, Seo, Chai: "JMJD2A attenuation affects cell cycle and tumourigenic inflammatory gene regulation in lipopolysaccharide stimulated neuroectodermal stem cells." dans: Experimental cell research, Vol. 328, Issue 2, pp. 361-78, (2014) (PubMed).

Dikopoltsev, Foltyn, Zehl, Jensen, Mori, Radzishevsky, Wolosker: "FBXO22 protein is required for optimal synthesis of the N-methyl-D-aspartate (NMDA) receptor coagonist D-serine." dans: The Journal of biological chemistry, Vol. 289, Issue 49, pp. 33904-15, (2014) (PubMed).

Hosseinzadeh Shirzeily, Pasbakhsh, Amidi, Mehrannia, Sobhani: "Comparison of differentiation potential of male mouse adipose tissue and bone marrow derived-mesenchymal stem cells into germ cells." dans: Iranian journal of reproductive medicine, Vol. 11, Issue 12, pp. 965-76, (2014) (PubMed).

Young, McDonald, Hendzel: "Kdm4b histone demethylase is a DNA damage response protein and confers a survival advantage following γ-irradiation." dans: The Journal of biological chemistry, Vol. 288, Issue 29, pp. 21376-88, (2013) (PubMed).

Kim, Shin, Berry, Oh, Janknecht: "The JMJD2A demethylase regulates apoptosis and proliferation in colon cancer cells." dans: Journal of cellular biochemistry, Vol. 113, Issue 4, pp. 1368-76, (2012) (PubMed).

Synonymes et noms alternatifs relatifs à KDM4A

lysine demethylase 4A (KDM4A), lysine-specific demethylase 4A (LOC100228023), lysine (K)-specific demethylase 4A (KDM4A), lysine (K)-specific demethylase 4A (Kdm4a), lysine demethylase 4A (Kdm4a), D4Ertd222e, JHDM3A, JMJD2, Jmjd2, JMJD2A, Jmjd2a, mKIAA0677, TDRD14A

Protein level used designations for KDM4A

  • jumonji domain containing 2A
  • lysine (K)-specific demethylase 4A
  • lysine-specific demethylase 4A
  • jumonji domain-containing protein 2A
  • JmjC domain-containing histone demethylation protein 3A
  • jumonji domain-containing 2A
  • lysine-specific demethylase 4A-like
  • jmjC domain-containing histone demethylation protein 3A
  • jumonji C domain-containing histone demethylase 3A
  • jumonji domain containing 2
  • tudor domain containing 14A
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