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KDM5A Produits

(Lysine (K)-Specific Demethylase 5A (KDM5A))

Catégories

The protein encoded by this gene is a ubiquitously expressed nuclear protein. It binds directly, with several other proteins, to retinoblastoma protein which regulates cell proliferation. This protein also interacts with rhombotin-2 which functions distinctly in erythropoiesis and in T-cell leukemogenesis. Rhombotin-2 is thought to either directly affect the activity of the encoded protein or may indirectly modulate the functions of the retinoblastoma protein by binding to this protein. [provided by RefSeq, Mar 2010].

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Catégories KDM5A en vedette

KDM5A Anticorps

High quality antibodies with extensive validation data.

KDM5A Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

KDM5A recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IF, FACS
Validations
  • (3)
  • (6)
N° du produit ABIN3201015
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, IP, ChIP
Validations
  • (4)
N° du produit ABIN7268330
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA
Validations
  • (3)
N° du produit ABIN562597
Quantité 100 μg
Fiche technique Fiche technique

KDM5A recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6975003
Quantité 96 tests
Fiche technique Fiche technique

KDM5A recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Baculovirus
Validations
  • (3)
N° du produit ABIN2669680
Quantité 20 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1308284
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN5709797
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits KDM5A

Mitsui, Yoshida, Shinoda, Matsumori, Tsujii, Tsuchida, Wada, Hasegawa, Ito, Mino, Onuki, Yoshida, Sasaki, Mizukami: "Identification of ryuvidine as a KDM5A inhibitor." dans: Scientific reports, Vol. 9, Issue 1, pp. 9952, (2019) (PubMed).

Eid, Abdel-Rehim: "Vitamin C promotes pluripotency of human induced pluripotent stem cells via the histone demethylase JARID1A." dans: Biological chemistry, Vol. 397, Issue 11, pp. 1205-1213, (2016) (PubMed).

Chai, Smith, Fitter, Mitchell, Pan, Ilicic, Maiti, Zakar, Madsen: "Increased progesterone receptor A expression in labouring human myometrium is associated with decreased promoter occupancy by the histone demethylase JARID1A." dans: Molecular human reproduction, Vol. 20, Issue 5, pp. 442-53, (2014) (PubMed).

Ge, Li, Wang, Liu, Zhu, Björkholm, Gruber, Xu: "Chromatin remodeling: recruitment of histone demethylase RBP2 by Mad1 for transcriptional repression of a Myc target gene, telomerase reverse transcriptase." dans: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 24, Issue 2, pp. 579-86, (2010) (PubMed).

Liefke, Oswald, Alvarado, Ferres-Marco, Mittler, Rodriguez, Dominguez, Borggrefe: "Histone demethylase KDM5A is an integral part of the core Notch-RBP-J repressor complex." dans: Genes & development, Vol. 24, Issue 6, pp. 590-601, (2010) (PubMed).

Lopez-Bigas, Kisiel, Dewaal, Holmes, Volkert, Gupta, Love, Murray, Young, Benevolenskaya: "Genome-wide analysis of the H3K4 histone demethylase RBP2 reveals a transcriptional program controlling differentiation." dans: Molecular cell, Vol. 31, Issue 4, pp. 520-30, (2008) (PubMed).

Tsai, Nguyen, Shi, Barton: "p53-targeted LSD1 functions in repression of chromatin structure and transcription in vivo." dans: Molecular and cellular biology, Vol. 28, Issue 17, pp. 5139-46, (2008) (PubMed).

Christensen, Agger, Cloos, Pasini, Rose, Sennels, Rappsilber, Hansen, Salcini, Helin: "RBP2 belongs to a family of demethylases, specific for tri-and dimethylated lysine 4 on histone 3." dans: Cell, Vol. 128, Issue 6, pp. 1063-76, (2007) (PubMed).

Klose, Yan, Tothova, Yamane, Erdjument-Bromage, Tempst, Gilliland, Zhang, Kaelin: "The retinoblastoma binding protein RBP2 is an H3K4 demethylase." dans: Cell, Vol. 128, Issue 5, pp. 889-900, (2007) (PubMed).

Synonymes et noms alternatifs relatifs à KDM5A

lysine demethylase 5A (Kdm5a), lysine demethylase 5A (KDM5A), lysine (K)-specific demethylase 5A (Kdm5a), AA409370, C76986, Jarid1a, JARID1A, RBBP-2, RBBP2, Rbbp2, RBP2

Protein level used designations for KDM5A

  • jumonji, AT rich interactive domain 1A (Rbp2 like)
  • lysine-specific demethylase 5A
  • jumonji, AT rich interactive domain 1A
  • lysine (K)-specific demethylase 5A
  • JARID1A variant protein-like
  • jumonji AT-rich interactive domain 1A
  • retinoblastoma binding protein 2
  • Jumonji, AT rich interactive domain 1A (RBP2-like)
  • histone demethylase JARID1A
  • jumonji/ARID domain-containing protein 1A
  • RBBP-2
  • retinoblastoma-binding protein 2
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