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KDM5B Produits

(Lysine (K)-Specific Demethylase 5B (KDM5B))

Catégories

Histone demethylase that demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9' or H3 'Lys-27'. Demethylates trimethylated, dimethylated and monomethylated H3 'Lys-4'. Acts as a transcriptional corepressor (By similarity).

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Catégories KDM5B en vedette

KDM5B Anticorps

High quality antibodies with extensive validation data.

KDM5B Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

KDM5B recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, ELISA, IF, IHC (p)
Validations
  • (3)
  • (8)
N° du produit ABIN1327126
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application ELISA, FACS
Validations
  • (4)
N° du produit ABIN5542656
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human, Rat
Application WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
  • (3)
N° du produit ABIN762986
Quantité 100 μL
Fiche technique Fiche technique

KDM5B recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Insect cells (Sf9)
Validations
  • (3)
N° du produit ABIN2669681
Quantité 20 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1308520
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Mouse
Source Baculovirus infected Insect Cells, Insect cells (Sf9), Mouse
Validations
N° du produit ABIN6700242
Quantité 50 μg
Fiche technique Fiche technique

Dernières publications sur nos produits KDM5B

Shannan, Matschke, Chauvistré, Vogel, Klein, Meier, Westphal, Bruns, Rauschenberg, Utikal, Forschner, Berking, Terheyden, Dabrowski, Gutzmer, Rafei-Shamsabadi, Meiss, Heinzerling, Zimmer, Livingstone et al.: "Sequence-dependent cross-resistance of combined radiotherapy plus BRAFV600E inhibition in melanoma. ..." dans: European journal of cancer (Oxford, England : 1990), Vol. 109, pp. 137-153, (2019) (PubMed).

Vogel, Bordag, Zügner, Trajkovic-Arsic, Chauvistré, Shannan, Váraljai, Horn, Magnes, Siveke, Schadendorf, Roesch: "Targeting the H3K4 demethylase KDM5B reprograms the metabolome and phenotype of melanoma cells." dans: The Journal of investigative dermatology, (2019) (PubMed).

Yuan, Liu, Li, Lan, Ma, Li, Kong, Sun, Hou, Hou, Ma, Ren, Zhou, Gao: "Blockade of Immune-Checkpoint B7-H4 and Lysine Demethylase 5B in Esophageal Squamous Cell Carcinoma Confers Protective Immunity against P. gingivalis Infection." dans: Cancer immunology research, Vol. 7, Issue 9, pp. 1440-1456, (2019) (PubMed).

Boyle, Fedele, Corbin, Wybacz, Szeto, Lewin, Young, Wong, Fuller, Spillane, Speakman, Donahoe, Pohl, Gyorki, Henderson, Johnstone, Papenfuss, Shackleton: "CD271 Expression on Patient Melanoma Cells Is Unstable and Unlinked to Tumorigenicity." dans: Cancer research, Vol. 76, Issue 13, pp. 3965-77, (2016) (PubMed).

Bamodu, Huang, Lee, Wu, Wang, Hsiao, Yeh, Chao: "Aberrant KDM5B expression promotes aggressive breast cancer through MALAT1 overexpression and downregulation of hsa-miR-448." dans: BMC cancer, Vol. 16, pp. 160, (2016) (PubMed).

Cui, Song, Hou, Han, Hu, Wu, Chen, Mao: "PLU-1/JARID1B overexpression predicts proliferation properties in head and neck squamous cell carcinoma." dans: Oncology reports, Vol. 33, Issue 5, pp. 2454-60, (2015) (PubMed).

Lu, Liu, Li, Xie, Adhiambo, Yang, Ballard, Nakayama, Matusik, Chen: "SKP2 inactivation suppresses prostate tumorigenesis by mediating JARID1B ubiquitination." dans: Oncotarget, Vol. 6, Issue 2, pp. 771-88, (2015) (PubMed).

Wang, Mao, Du, He, Han: "Overexpression of JARID1B is associated with poor prognosis and chemotherapy resistance in epithelial ovarian cancer." dans: Tumour biology, Vol. 36, Issue 4, pp. 2465-72, (2015) (PubMed).

Klein, Piao, Xi, Rincon-Arano, Rothbart, Peng, Wen, Larson, Zhang, Zheng, Cortazar, Peña, Mangan, Bentley, Strahl, Groudine, Li, Shi, Kutateladze: "The histone-H3K4-specific demethylase KDM5B binds to its substrate and product through distinct PHD fingers." dans: Cell reports, Vol. 6, Issue 2, pp. 325-35, (2014) (PubMed).

Stanisz, Saul, Müller, Kappl, Niemeyer, Vogt, Hoth, Roesch, Bogeski: "Inverse regulation of melanoma growth and migration by Orai1/STIM2-dependent calcium entry." dans: Pigment cell & melanoma research, Vol. 27, Issue 3, pp. 442-53, (2014) (PubMed).

Synonymes et noms alternatifs relatifs à KDM5B

lysine (K)-specific demethylase 5Ba (kdm5ba), lysine (K)-specific demethylase 5Bb (kdm5bb), lysine demethylase 5B (KDM5B), lysine (K)-specific demethylase 5B (Kdm5b), lysine (K)-specific demethylase 5B (KDM5B), lysine demethylase 5B (Kdm5b), 2010009J12Rik, 2210016I17Rik, AW556288, cb264, CT31, D1Ertd202e, id:ibd5050, jarid1b, JARID1B, Jarid1b, jarid1ba, jarid1bb, mKIAA4034, PLU-1, plu1, PLU1, Plu1, PUT1, Rb-Bp2, RBBP2H1A, RGD1565602, wu:fc44h11, wu:fd15c05, zgc:85741

Protein level used designations for KDM5B

  • jumonji, AT rich interactive domain 1B (Rbp2 like)
  • jumonji, AT rich interactive domain 1Ba (Rbp2 like)
  • histone demethylase JARID1B-B
  • jumonji/ARID domain-containing protein 1B-B
  • lysine-specific demethylase 5B-B
  • putative DNA/chromatin binding motif
  • lysine (K)-specific demethylase 5B
  • Jumonji, AT rich interactive domain 1B (RBP2-like)
  • jumonji, AT rich interactive domain 1B
  • lysine-specific demethylase 5B-like
  • RBP2-H1
  • cancer/testis antigen 31
  • histone demethylase JARID1B
  • jumonji/ARID domain-containing protein 1B
  • lysine-specific demethylase 5B
  • retinoblastoma-binding protein 2 homolog 1
  • retinoblastoma-binding protein 2, homolog 1A
  • putative DNA/chromatin binding motif 1
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