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KEAP1 Produits

(Kelch-Like ECH-Associated Protein 1 (KEAP1))
This gene encodes a protein containing KELCH-1 like domains, as well as a BTB/POZ domain. Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus. This interaction results in the expression of the catalytic subunit of gamma-glutamylcysteine synthetase. Two alternatively spliced transcript variants encoding the same isoform have been found for this gene. [provided by RefSeq, Jul 2008].

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Catégories KEAP1 en vedette

KEAP1 Anticorps

High quality antibodies with extensive validation data.

KEAP1 Kits ELISA

Reliable ELISA kits for a wide range of species.

KEAP1 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

KEAP1 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application ELISA, IHC, FACS
Validations
  • (2)
  • (5)
N° du produit ABIN1098141
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application ELISA, ICC, FACS
Validations
  • (2)
  • (5)
N° du produit ABIN1098137
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human, Mouse
Application WB, IHC, IHC (p), FACS
Validations
  • (8)
N° du produit ABIN1499016
Quantité 100 μL
Fiche technique Fiche technique

KEAP1 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (2)
  • (1)
N° du produit ABIN6957270
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6968103
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6975693
Quantité 96 tests
Fiche technique Fiche technique

KEAP1 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
  • (1)
N° du produit ABIN1308530
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (21)
  • (1)
N° du produit ABIN2724103
Quantité 20 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN7123669
Quantité 50 μg
Fiche technique Fiche technique

Dernières publications sur nos produits KEAP1

Jastrząb, Gęgotek, Skrzydlewska: "Cannabidiol Regulates the Expression of Keratinocyte Proteins Involved in the Inflammation Process through Transcriptional Regulation." dans: Cells, Vol. 8, Issue 8, (2020) (PubMed).

Han, Shi, Du, Shi, Zhang, Zheng, Xu, Jiang: "Schisandrin C targets Keap1 and attenuates oxidative stress by activating Nrf2 pathway in Ang II-challenged vascular endothelium." dans: Phytotherapy research : PTR, Vol. 33, Issue 3, pp. 779-790, (2019) (PubMed).

Xiang, Ye, Huang, Yu, Chen, Deng, Zhang, Lou, Zhang, Shi, Chen, Zhou: "Brusatol Enhances the Chemotherapy Efficacy of Gemcitabine in Pancreatic Cancer via the Nrf2 Signalling Pathway." dans: Oxidative medicine and cellular longevity, Vol. 2018, pp. 2360427, (2018) (PubMed).

Kabel, Alzahrani, Bawazir, Khawtani, Arab: "Targeting the proinflammatory cytokines, oxidative stress, apoptosis and TGF-β1/STAT-3 signaling by irbesartan to ameliorate doxorubicin-induced hepatotoxicity." dans: Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, Vol. 24, Issue 8, pp. 623-631, (2018) (PubMed).

Kabel, Abd Elmaaboud, Atef, Baali: "Ameliorative potential of linagliptin and/or calcipotriol on bleomycin-induced lung fibrosis: In vivo and in vitro study." dans: Environmental toxicology and pharmacology, Vol. 50, pp. 216-226, (2017) (PubMed).

Su, Liu, Wang, Wang, Song, Song: "The electrophilic character of quinones is essential for the suppression of Bach1." dans: Toxicology, Vol. 387, pp. 17-26, (2017) (PubMed).

Chen, Li, Fan, Cao, Yao, Xu: "Selenium antagonizes cadmium-induced apoptosis in chicken spleen but not involving Nrf2-regulated antioxidant response." dans: Ecotoxicology and environmental safety, Vol. 145, pp. 503-510, (2017) (PubMed).

Kouam, Yuan, Njayou, He, Tsayem, Oladejo, Song, Moundipa, Gao: "Induction of Mkp-1 and Nuclear Translocation of Nrf2 by Limonoids from Khaya grandifoliola C.DC Protect L-02 Hepatocytes against Acetaminophen-Induced Hepatotoxicity." dans: Frontiers in pharmacology, Vol. 8, pp. 653, (2017) (PubMed).

Chen, Lin, Liu, Hsu, Lin, Su: "Caveolin-1 Expression Ameliorates Nephrotic Damage in a Rabbit Model of Cholesterol-Induced Hypercholesterolemia." dans: PLoS ONE, Vol. 11, Issue 4, pp. e0154210, (2016) (PubMed).

Lutz, Pace, Arnold: "Rotavirus NSP1 Associates with Components of the Cullin RING Ligase Family of E3 Ubiquitin Ligases." dans: Journal of virology, Vol. 90, Issue 13, pp. 6036-48, (2016) (PubMed).

Synonymes et noms alternatifs relatifs à KEAP1

kelch like ECH associated protein 1 (KEAP1), kelch-like ECH-associated protein 1 (Keap1), Kelch-like ECH-associated protein 1 (Keap1), kelch-like ECH-associated protein 1a (keap1a), kelch like ECH associated protein 1 (keap1), kelch like ECH associated protein 1 L homeolog (keap1.L), kelch like ECH associated protein 1 (Keap1), kelch-like ECH-associated protein 1b (keap1b), fb36f11, INrf2, INRF2, Inrf2, keap1, KEAP1, KLHL19, klhl19, mKIAA0132, wu:fb36f11, zgc:171654

Protein level used designations for KEAP1

  • cytosolic inhibitor of Nrf2
  • kelch-like family member 19
  • kelch-like protein 19
  • NRF2 cytosolic inhibitor
  • ring canal protein
  • kelch-like ECH-associated protein 1
  • klhl19
  • LOW QUALITY PROTEIN: kelch-like ECH-associated protein 1
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