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KIR2DL1 Produits

(Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 1 (KIR2DL1))

Catégories

Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several 'framework' genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules\\\\; thus, KIR proteins are thought to play an important role in regulation of the immune response. [provided by RefSeq, Jul 2008].

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Catégories KIR2DL1 en vedette

KIR2DL1 Anticorps

High quality antibodies with extensive validation data.

KIR2DL1 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

KIR2DL1 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application ELISA, IHC, IF
Validations
  • (2)
N° du produit ABIN7157495
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, IP
Validations
  • (2)
N° du produit ABIN165422
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IP
Validations
  • (3)
N° du produit ABIN2789507
Quantité 100 μL
Fiche technique Fiche technique

KIR2DL1 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN6730430
Quantité 96 tests
Fiche technique Fiche technique

KIR2DL1 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (2)
N° du produit ABIN7275084
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (2)
N° du produit ABIN7275085
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1308691
Quantité 10 μg
Fiche technique Fiche technique

Dernières publications sur nos produits KIR2DL1

Collins, Rothman, Liu, Reiner: "Eomesodermin and T-bet mark developmentally distinct human natural killer cells." dans: JCI insight, Vol. 2, Issue 5, pp. e90063, (2017) (PubMed).

Blom, Braun, Pakalniene, Lunemann, Enqvist, Dailidyte, Schaffer, Lindquist, Mickiene, Michaëlsson, Ljunggren, Gredmark-Russ: "NK Cell Responses to Human Tick-Borne Encephalitis Virus Infection." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 197, Issue 7, pp. 2762-71, (2016) (PubMed).

Rettman, Willem, David, Riou, Legrand, Esbelin, Cesbron, Senitzer, Gagne, Retière: "New insights on the natural killer cell repertoire from a thorough analysis of cord blood cells." dans: Journal of leukocyte biology, Vol. 100, Issue 3, pp. 471-9, (2016) (PubMed).

Horowitz, Guethlein, Nemat-Gorgani, Norman, Cooley, Miller, Parham: "Regulation of Adaptive NK Cells and CD8 T Cells by HLA-C Correlates with Allogeneic Hematopoietic Cell Transplantation and with Cytomegalovirus Reactivation." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 195, Issue 9, pp. 4524-36, (2015) (PubMed).

Marquardt, Ivarsson, Blom, Gonzalez, Braun, Falconer, Gustafsson, Fogdell-Hahn, Sandberg, Michaëlsson: "The Human NK Cell Response to Yellow Fever Virus 17D Is Primarily Governed by NK Cell Differentiation Independently of NK Cell Education." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 195, Issue 7, pp. 3262-72, (2015) (PubMed).

Dunphy, Guinan, Chorcora, Jayaraman, Traherne, Trowsdale, Pende, Middleton, Gardiner: "2DL1, 2DL2 and 2DL3 all contribute to KIR phenotype variability on human NK cells." dans: Genes and immunity, Vol. 16, Issue 5, pp. 301-10, (2015) (PubMed).

Pesce, Carlomagno, Moretta, Sivori, Marcenaro: "Uptake of CCR7 by KIR2DS4⁺ NK cells is induced upon recognition of certain HLA-C alleles." dans: Journal of immunology research, Vol. 2015, pp. 754373, (2015) (PubMed).

Sharkey, Xiong, Kennedy, Gardner, Farrell, Chazara, Ivarsson, Hiby, Colucci, Moffett: "Tissue-Specific Education of Decidual NK Cells." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 195, Issue 7, pp. 3026-32, (2015) (PubMed).

Enqvist, Ask, Forslund, Carlsten, Abrahamsen, Béziat, Andersson, Schaffer, Spurkland, Bryceson, Önfelt, Malmberg: "Coordinated expression of DNAM-1 and LFA-1 in educated NK cells." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 194, Issue 9, pp. 4518-27, (2015) (PubMed).

Marquardt, Béziat, Nyström, Hengst, Ivarsson, Kekäläinen, Johansson, Mjösberg, Westgren, Lankisch, Wedemeyer, Ellis, Ljunggren, Michaëlsson, Björkström: "Cutting edge: identification and characterization of human intrahepatic CD49a+ NK cells." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 194, Issue 6, pp. 2467-71, (2015) (PubMed).

Synonymes et noms alternatifs relatifs à KIR2DL1

killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 1 (KIR2DL1), killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1 (KIR2DL1), CD158A, KIR-K64, KIR221, NKAT, NKAT1, p58.1

Protein level used designations for KIR2DL1

  • CD158 antigen-like family member A
  • MHC class I NK cell receptor
  • NKAT-1
  • killer Ig receptor
  • killer cell immunoglobulin-like receptor 2DL1
  • killer inhibitory receptor 2-2-1
  • natural killer-associated transcript 1
  • p58 NK cell inhibitory receptor NKR-K6
  • p58 NK receptor CL-42/47.11
  • p58 killer cell inhibitory receptor KIR-K64
  • p58 natural killer cell receptor clones CL-42/47.11
  • p58.1 MHC class-I-specific NK receptor
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