KIR2DL5B Produits
(Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 5B (KIR2DL5B))
Catégories
Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several 'framework' genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules\\; thus, KIR proteins are thought to play an important role in regulation of the immune response. [provided by RefSeq, Jul 2008].
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Catégories KIR2DL5B en vedette
KIR2DL5B Anticorps
High quality antibodies with extensive validation data.
KIR2DL5B recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, FACS, IHC (p)
Validations
- (3)
N° du produit
ABIN652855
Quantité
400 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
ELISA, IF
Validations
- (1)
N° du produit
ABIN7183707
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
ELISA, WB, IF
Validations
N° du produit
ABIN7186155
Quantité
100 μg
Fiche technique
Fiche technique
Synonymes et noms alternatifs relatifs à KIR2DL5B
killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 5B (KIR2DL5B), KIR2DL5, KIR2DL5.2, KIR2DLXProtein level used designations for KIR2DL5B
- CD158 antigen-like family member F2
- killer cell Ig-like receptor
- killer cell immunoglobulin-like receptor 2DL5B
- killer cell immunoglobulin-like receptor 2DLX
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