KIR2DS2 Produits
(Killer Cell Immunoglobulin-Like Receptor 2DS2 (KIR2DS2))
Catégories
Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several 'framework' genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules\\\\; thus, KIR proteins are thought to play an important role in regulation of the immune response. [provided by RefSeq, Jul 2008].
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Catégories KIR2DS2 en vedette
KIR2DS2 Anticorps
High quality antibodies with extensive validation data.
KIR2DS2 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
KIR2DS2 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
ELISA, IHC, IF
Validations
- (3)
N° du produit
ABIN7157511
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, FACS, IHC (p)
Validations
- (3)
N° du produit
ABIN651951
Quantité
400 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC, ICC
Validations
- (3)
N° du produit
ABIN1859539
Quantité
100 μL
Fiche technique
Fiche technique
KIR2DS2 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7403846
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN3010362
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
N° du produit
ABIN2724252
Quantité
20 μg
Fiche technique
Fiche technique
Synonymes et noms alternatifs relatifs à KIR2DS2
killer cell immunoglobulin like receptor, two Ig domains and short cytoplasmic tail 2 (KIR2DS2), 183ActI, CD158b, CD158J, cl-49, NKAT5Protein level used designations for KIR2DS2
- 1060P11.9.2
- CD158 antigen-like family member J
- MHC class I NK cell receptor
- NK receptor 183 ActI
- NKAT-5
- killer cell immunoglobulin-like receptor 2DS2
- killer-cell Ig-like receptor
- killer-cell immunoglobulin-like receptor two domains short tail 2 protein
- natural killer associated transcript 5
- natural killer cell inhibitory receptor
- natural killer-associated transcript 5
- p58 KIR
- p58 NK receptor CL-49
- p58 killer cell inhibitory receptor KIR-K7a
- p58 natural killer cell receptor clone CL-49
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