KIR3DL2 Produits
(Killer Cell Immunoglobulin-Like Receptor, three Domains, Long Cytoplasmic Tail, 2 (KIR3DL2))
Catégories
Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several 'framework' genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules\\\\; thus, KIR proteins are thought to play an important role in regulation of the immune response. This gene is one of the 'framework' loci that is present on all haplotypes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jun 2011].
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Catégories KIR3DL2 en vedette
KIR3DL2 Anticorps
High quality antibodies with extensive validation data.
KIR3DL2 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
KIR3DL2 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
IHC, ELISA
Validations
- (3)
N° du produit
ABIN7189471
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IF, ICC
Validations
- (2)
N° du produit
ABIN2856893
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
ELISA, IF
Validations
- (1)
N° du produit
ABIN7157528
Quantité
100 μg
Fiche technique
Fiche technique
KIR3DL2 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
HEK-293 Cells
Validations
- (3)
N° du produit
ABIN7275102
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Rhesus Monkey
Source
HEK-293 Cells
Validations
- (2)
N° du produit
ABIN7275101
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7403849
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits KIR3DL2
: "Human NK Cells Downregulate Zap70 and Syk in Response to Prolonged Activation or DNA Damage." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 200, Issue 3, pp. 1146-1158, (2018) (PubMed).: "α3-Deletion Isoform of HLA-A11 Modulates Cytotoxicity of NK Cells: Correlations with HIV-1 Infection of Cells." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 199, Issue 6, pp. 2030-2042, (2017) (PubMed).
: "The Incubation Period of Primary Epstein-Barr Virus Infection: Viral Dynamics and Immunologic Events." dans: PLoS pathogens, Vol. 11, Issue 12, pp. e1005286, (2015) (PubMed).
: "Contenders in FasL/TNF death signaling." dans: Cell, Vol. 81, Issue 4, pp. 479-82, (1995) (PubMed).
Synonymes et noms alternatifs relatifs à KIR3DL2
killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 2 (KIR3DL2), CD158K, NKAT-4, NKAT4, NKAT4B, p140Protein level used designations for KIR3DL2
- CD158 antigen-like family member K
- KIR antigen 3DL2
- MHC class I NK cell receptor
- killer Ig receptor
- killer cell immunoglobulin-like receptor 3DL2
- killer cell immunoglobulin-like receptor KIR3DL2
- natural killer cell inhibitory receptor
- natural killer-associated transcript 4
- p70 NK receptor CL-5
- p70 killer cell inhibitory receptor
- p70 natural killer cell receptor clone CL-5
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