SensoLyte® AMC Caspase Substrate Sampler Kit

N° du produit ABIN1882428

Détail du produit

Antigène: Caspase (CASP)

Méthode de détection: Fluorometric

Application: Fluorescence Resonance Energy Transfer Microscopy (FRET)

Marque: SensoLyte®

Attributs du produit: The SensoLyte® Caspase Substrate Kit contains a series of AMC-based peptide substrates as fluorogenic indicators for assaying caspase protease activities. It provides the best solution for identifying a suitable substrate for designing AMC-based caspase assays. All the components in the kit are available in bulk package.

Information d'application

Commentaires:

FRET-based Assay Kit

Restrictions: For Research Use only

Stockage

Conseil sur la manipulation: Keep Components A and B away from light

Stock: -20 °C

Référence

B?dziul, Jakubowicz-Gil, Paduch, G?owniak, Gawron: "Combined treatment with quercetin and imperatorin as a potent strategy for killing HeLa and Hep-2 cells." dans: Molecular and cellular biochemistry, Vol. 392, Issue 1-2, pp. 213-27, (2014) (PubMed).

B?dziul, Jakubowicz-Gil, Langner, Rzeski, G?owniak, Gawron: "The effect of quercetin and imperatorin on programmed cell death induction in T98G cells in vitro." dans: Pharmacological reports : PR, Vol. 66, Issue 2, pp. 292-300, (2014) (PubMed).

Jakubowicz-Gil, Langner, B?dziul, Wertel, Rzeski: "Apoptosis induction in human glioblastoma multiforme T98G cells upon temozolomide and quercetin treatment." dans: Tumour biology, Vol. 34, Issue 4, pp. 2367-78, (2013) (PubMed).

Détail du antigène

Antigène: Caspase (CASP)

Autre désignation: Caspase (CASP Produits)

Synonymes: CG5370 Kit, DCP-1 Kit, DCP1 Kit, Dcp1 Kit, Dmel\\CG5370 Kit, ccp1 Kit, dcp-1 Kit, dcp1 Kit, l(2)01862 Kit, l(2)02132 Kit, Death caspase-1 Kit, Dcp-1 Kit

Sujet: Caspases play important roles in apoptosis and cell signaling. They are also identified as drug-screening targets. AMC-based substrates yield blue fluorescence upon protease cleavage (Ex/Em=354 nm/442 nm). They are widely used to monitor caspase activity.