Thymic Stromal Lymphopoietin Kit ELISA
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- Antigène Voir toutes Thymic Stromal Lymphopoietin (TSLP) Kits ELISA
- Thymic Stromal Lymphopoietin (TSLP)
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Reactivité
- Humain
- Méthode de détection
- Colorimetric
- Type de méthode
- Sandwich ELISA
- Gamme de detection
- 3.9-250 pg/mL
- Seuil minimal de détection
- 3.9 pg/mL
- Application
- ELISA
- Type d'échantillon
- Cell Culture Supernatant, Serum, Plasma (heparin), Plasma (citrate), Plasma (EDTA)
- Analytical Method
- Quantitative
- Specificité
- Natural and recombinant Human TSLP Ligand
- Sensibilité
- 2 pg/mL
- Matériel non inclus
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- Microplate reader.
- Pipettes and pipette tips.
- EP tube Deionized or distilled water.
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- Indications d'application
- Detection Wavelength: 450 nm
- Volume d'échantillon
- 20 μL
- Durée du test
- 3 h
- Plaque
- Pre-coated
- Restrictions
- For Research Use only
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- Stock
- 4 °C
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- Antigène Voir toutes Thymic Stromal Lymphopoietin (TSLP) Kits ELISA
- Thymic Stromal Lymphopoietin (TSLP)
- Autre désignation
- TSLP (TSLP Produits)
- Sujet
- Thymic Stromal Lymphopoietin (TSLP) is a 23 kDa member of the IL-7 family of a-helical cytokines (1-3). It is a monomeric glycoprotein that is synthesized as a 159 amino acid (aa) precursor (4, 5). TSLP appears to have species-specific functions. In mouse, TSLP was initially reported to act on NK cells, mast cells, and B cells, but this does not appear to occur in humans. In humans, TSLP is produced by a number of divergent cell types, all of which appear to target T cells, monocytes, and/or dendritic cells (2). On TCR-activated T cells, TSLP directly induces T cell proliferation (6). The significance of this direct action is unclear. On monocytes, TSLP is reported to induce the release of multiple chemokines that target CCR4, a receptor associated with the Th2 subset (5). TSLP is best known for its direct action on subsets of dendritic cells. In thymic medulla, Hassell
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