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TIMP3 Kit ELISA

TIMP3 Reactivité: Porc AA 24-211 Colorimetric Sandwich ELISA
N° du produit ABIN5510571
  • Antigène Voir toutes TIMP3 Kits ELISA
    TIMP3 (TIMP Metallopeptidase Inhibitor 3 (TIMP3))
    Épitope
    AA 24-211
    Reactivité
    • 11
    • 7
    • 6
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    Porc
    Méthode de détection
    Colorimetric
    Type de méthode
    Sandwich ELISA
    Application
    ELISA
    Fonction
    Sandwich High Sensitivity ELISA kit for Quantitative Detection of Pig porcine TIMP-3
    Marque
    PicoKine™
    Analytical Method
    Quantitative
    Specificité
    Expression system for standard: NSO
    Immunogen sequence: C24-P211
    Réactivité croisée (Details)
    There is no detectable cross-reactivity with other relevant proteins.
    Attributs du produit

    Sequence similarities: Belongs to the protease inhibitor I35 (TIMP) family.

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  • Plaque
    Pre-coated
    Restrictions
    For Research Use only
  • Stock
    4 °C,-20 °C
    Stockage commentaire
    Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)
    Date de péremption
    12 months
  • Antigène Voir toutes TIMP3 Kits ELISA
    TIMP3 (TIMP Metallopeptidase Inhibitor 3 (TIMP3))
    Autre désignation
    TIMP3 (TIMP3 Produits)
    Synonymes
    TIMP-3 Kit ELISA, TIMP3 Kit ELISA, timp3 Kit ELISA, HSMRK222 Kit ELISA, K222 Kit ELISA, K222TA2 Kit ELISA, SFD Kit ELISA, IMP-3 Kit ELISA, timp3-A Kit ELISA, Timp-3 Kit ELISA, metalloproteinase inhibitor 3 Kit ELISA, TIMP metallopeptidase inhibitor 3 Kit ELISA, Metalloproteinase inhibitor 3 Kit ELISA, TIMP metallopeptidase inhibitor 3 L homeolog Kit ELISA, tissue inhibitor of metalloproteinase 3 Kit ELISA, CpipJ_CPIJ003282 Kit ELISA, TIMP3 Kit ELISA, timp3 Kit ELISA, Timp3 Kit ELISA, timp3.L Kit ELISA
    Sujet

    Protein Function: Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. May form part of a tissue-specific acute response to remodeling stimuli. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-9, MMP-13, MMP-14 and MMP-15.

    Background: The tissue inhibitors of metalloproteinases(TIMPs) are natural inhibitors of the matrix metalloproteinases, a group of zinc-binding endopeptidases involved in the degradation of the extracellular matrix. The TIMP3 gene is expressed in many tissues, with highest expression in the placenta. TIMP3 encodes a potent angiogenesis inhibitor and is mutated in Sorsby fundus dystrophy, a macular degenerative disease with submacular choroidal neovascularization. TIMP3 gene is mapped to 22q12.1-q13.2. Mutations in TIMP3 cause the autosomal dominant disorder Sorsby's fundus dystrophy(SFD).

    Synonyms: Metalloproteinase inhibitor 3,Protein MIG-5,Tissue inhibitor of metalloproteinases 3,TIMP-3,TIMP3,

    Full Gene Name: Metalloproteinase inhibitor 3

    Cellular Localisation: Secreted, extracellular space, extracellular matrix.
    UniProt
    P35625
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