LGALS1/Galectin 1 Kit ELISA
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- Antigène Voir toutes LGALS1/Galectin 1 (LGALS1) Kits ELISA
- LGALS1/Galectin 1 (LGALS1) (Lectin, Galactoside-Binding, Soluble, 1 (LGALS1))
- Épitope
- AA 2-135
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Reactivité
- Humain
- Méthode de détection
- Colorimetric
- Type de méthode
- Sandwich ELISA
- Application
- ELISA
- Fonction
- Sandwich High Sensitivity ELISA kit for Quantitative Detection of Human Galectin-1
- Marque
- PicoKine™
- Analytical Method
- Quantitative
- Specificité
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Expression system for standard: E.coli
Immunogen sequence: A2-D135 - Réactivité croisée (Details)
- There is no detectable cross-reactivity with other relevant proteins.
- Attributs du produit
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Tissue Specificity: Expressed in placenta, maternal decidua and fetal membranes. Within placenta, expressed in trophoblasts, stromal cells, villous endothelium, syncytiotrophoblast apical membrane and villous stroma. Within fetal membranes, expressed in amnion, chorioamniotic mesenchyma and chorion (at protein level). Expressed in cardiac, smooth, and skeletal muscle, neurons, thymus, kidney and hematopoietic cells. .
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- Discover our best selling LGALS1 Kit ELISA
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- Discover our top product LGALS1 Kit ELISA
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- Plaque
- Pre-coated
- Restrictions
- For Research Use only
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- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)
- Date de péremption
- 12 months
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MiRNA-22 inhibits oncogene galectin-1 in hepatocellular carcinoma." dans: Oncotarget, Vol. 7, Issue 35, pp. 57099-57116, (2018) (PubMed).
: "Galectin-1 from cancer-associated fibroblasts induces epithelial-mesenchymal transition through β1 integrin-mediated upregulation of Gli1 in gastric cancer." dans: Journal of experimental & clinical cancer research : CR, Vol. 35, Issue 1, pp. 175, (2017) (PubMed).
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MiRNA-22 inhibits oncogene galectin-1 in hepatocellular carcinoma." dans: Oncotarget, Vol. 7, Issue 35, pp. 57099-57116, (2018) (PubMed).
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- Antigène Voir toutes LGALS1/Galectin 1 (LGALS1) Kits ELISA
- LGALS1/Galectin 1 (LGALS1) (Lectin, Galactoside-Binding, Soluble, 1 (LGALS1))
- Autre désignation
- LGALS1 (LGALS1 Produits)
- Synonymes
- GAL1 Kit ELISA, GBP Kit ELISA, Galectin-1 Kit ELISA, LGAS1 Kit ELISA, LGALS1 Kit ELISA, MGC64502 Kit ELISA, GB10026 Kit ELISA, AA410090 Kit ELISA, Gal-1 Kit ELISA, Galbp Kit ELISA, L-14.5 Kit ELISA, L14 Kit ELISA, Lect14 Kit ELISA, galectin-1 Kit ELISA, Galaptin Kit ELISA, galectin 1 Kit ELISA, galectin-1 Kit ELISA, lectin, galactoside-binding, soluble, 1 L homeolog Kit ELISA, protein enabled Kit ELISA, lectin, galactose binding, soluble 1 Kit ELISA, LGALS1 Kit ELISA, Lgals1 Kit ELISA, CC1G_05003 Kit ELISA, CC1G_05004 Kit ELISA, lgals1.L Kit ELISA, LOC408848 Kit ELISA
- Sujet
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Protein Function: May regulate apoptosis, cell proliferation and cell differentiation. Binds beta-galactoside and a wide array of complex carbohydrates. Inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of Lyn kinase. Strong inducer of T-cell apoptosis. .
Background: Galectin-1 is a protein that in humans is encoded by the LGALS1 gene. The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. Galectin-1 may act as an autocrine negative growth factor that regulates cell proliferation. Its expression in Hodgkin Lymphoma has also been shown to mediate immunosuppression of CD8+ T-cells. Additionally, Galectin-1 is thought to play a role in creating immune tolerance in pregnancy.
Synonyms: Galectin-1,Gal-1,14 kDa laminin-binding protein,HLBP14,14 kDa lectin,Beta-galactoside-binding lectin L-14-I,Galaptin,HBL,HPL,Lactose-binding lectin 1,Lectin galactoside-binding soluble 1,Putative MAPK-activating protein PM12,S-Lac lectin 1,LGALS1,
Full Gene Name: Galectin-1
Cellular Localisation: Secreted, extracellular space, extracellular matrix. - UniProt
- P09382
- Pathways
- Carbohydrate Homeostasis
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