Sclerostin Kit ELISA
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- Antigène Voir toutes Sclerostin (SOST) Kits ELISA
- Sclerostin (SOST)
- Épitope
- AA 24-213
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Reactivité
- Humain
- Méthode de détection
- Colorimetric
- Type de méthode
- Sandwich ELISA
- Application
- ELISA
- Fonction
- Sandwich High Sensitivity ELISA kit for Quantitative Detection of Human Sclerostin/SOST
- Marque
- PicoKine™
- Analytical Method
- Quantitative
- Specificité
- Expression system for standard: NSO, Immunogen sequence: Q24-Y213
- Réactivité croisée (Details)
- There is no detectable cross-reactivity with other relevant proteins.
- Attributs du produit
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Tissue Specificity: Widely expressed at low levels with highest levels in bone, cartilage, kidney, liver, bone marrow and primary osteoblasts differentiated for 21 days. Detected in the subendothelial layer of the aortic intima (at protein level). .
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- Plaque
- Pre-coated
- Restrictions
- For Research Use only
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- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)
- Date de péremption
- 12 months
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- Antigène Voir toutes Sclerostin (SOST) Kits ELISA
- Sclerostin (SOST)
- Autre désignation
- SOST (SOST Produits)
- Synonymes
- LOC100313724 Kit ELISA, CDD Kit ELISA, VBCH Kit ELISA, 5430411E23Rik Kit ELISA, sclerostin Kit ELISA, LOC100313724 Kit ELISA, SOST Kit ELISA, Sost Kit ELISA
- Sujet
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Protein Function: Negative regulator of bone growth that acts through inhibition of Wnt signaling and bone formation. .
Background: Sclerostin is a protein that in humans is encoded by the SOST gene. It is a secreted glycoprotein with a C-terminal cysteine knot-like (CTCK) domain and sequence similarity to the DAN (differential screening-selected gene aberrative in neuroblastoma) family of bone morphogenetic protein (BMP) antagonists. Additionally, Sclerostin is produced by the osteocyte and has anti-anabolic effects on bone formation. The SOST gene maps to chromosome 17q12-q21.
Synonyms: Sclerostin,SOST,UNQ2976/PRO7455/PRO7476,
Full Gene Name: Sclerostin
Cellular Localisation: Secreted, extracellular space, extracellular matrix. - UniProt
- Q9BQB4
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