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Sclerostin Kit ELISA

SOST Reactivité: Humain AA 24-213 Colorimetric Sandwich ELISA
N° du produit ABIN5510605
  • Antigène Voir toutes Sclerostin (SOST) Kits ELISA
    Sclerostin (SOST)
    Épitope
    AA 24-213
    Reactivité
    • 8
    • 6
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Méthode de détection
    Colorimetric
    Type de méthode
    Sandwich ELISA
    Application
    ELISA
    Fonction
    Sandwich High Sensitivity ELISA kit for Quantitative Detection of Human Sclerostin/SOST
    Marque
    PicoKine™
    Analytical Method
    Quantitative
    Specificité
    Expression system for standard: NSO, Immunogen sequence: Q24-Y213
    Réactivité croisée (Details)
    There is no detectable cross-reactivity with other relevant proteins.
    Attributs du produit

    Tissue Specificity: Widely expressed at low levels with highest levels in bone, cartilage, kidney, liver, bone marrow and primary osteoblasts differentiated for 21 days. Detected in the subendothelial layer of the aortic intima (at protein level). .

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  • Plaque
    Pre-coated
    Restrictions
    For Research Use only
  • Stock
    4 °C,-20 °C
    Stockage commentaire
    Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)
    Date de péremption
    12 months
  • Antigène Voir toutes Sclerostin (SOST) Kits ELISA
    Sclerostin (SOST)
    Autre désignation
    SOST (SOST Produits)
    Synonymes
    LOC100313724 Kit ELISA, CDD Kit ELISA, VBCH Kit ELISA, 5430411E23Rik Kit ELISA, sclerostin Kit ELISA, LOC100313724 Kit ELISA, SOST Kit ELISA, Sost Kit ELISA
    Sujet

    Protein Function: Negative regulator of bone growth that acts through inhibition of Wnt signaling and bone formation. .

    Background: Sclerostin is a protein that in humans is encoded by the SOST gene. It is a secreted glycoprotein with a C-terminal cysteine knot-like (CTCK) domain and sequence similarity to the DAN (differential screening-selected gene aberrative in neuroblastoma) family of bone morphogenetic protein (BMP) antagonists. Additionally, Sclerostin is produced by the osteocyte and has anti-anabolic effects on bone formation. The SOST gene maps to chromosome 17q12-q21.

    Synonyms: Sclerostin,SOST,UNQ2976/PRO7455/PRO7476,

    Full Gene Name: Sclerostin

    Cellular Localisation: Secreted, extracellular space, extracellular matrix.
    UniProt
    Q9BQB4
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