TGFB2 Kit ELISA

N° du produit ABIN5510609

Détail du produit TGFB2 Kit ELISA

Antigène: TGFB2 (Transforming Growth Factor, beta 2 (TGFB2))

Épitope: AA 303-414

Reactivité: Cheval

Méthode de détection: Colorimetric

Type de méthode: Sandwich ELISA

Application: ELISA

Fonction: Sandwich High Sensitivity ELISA kit for Quantitative Detection of activated horse equine TGF-beta 2

Marque: PicoKine™

Analytical Method: Quantitative

Specificité: Expression system for standard: NSO
Immunogen sequence: A303-S414

Réactivité croisée (Details): There is no detectable cross-reactivity with other relevant proteins.

Attributs du produit:

Sequence similarities: Belongs to the TGF-beta family.

Information d'application

Plaque: Pre-coated

Restrictions: For Research Use only

Stockage

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)

Date de péremption: 12 months

Détail du antigène

Antigène: TGFB2 (Transforming Growth Factor, beta 2 (TGFB2))

Autre désignation: TGFB2 (TGFB2 Produits)

Synonymes: LDS4 Kit ELISA, TGF-beta2 Kit ELISA, tgf-beta2 Kit ELISA, tgfb2-A Kit ELISA, BB105277 Kit ELISA, Tgf-beta2 Kit ELISA, Tgfb-2 Kit ELISA, TGF-beta 2 Kit ELISA, Tgfbr2T Kit ELISA, TGFB2 Kit ELISA, TGFbeta2 Kit ELISA, MGF Kit ELISA, TGF-B2 Kit ELISA, transforming growth factor beta 2 Kit ELISA, transforming growth factor beta 2 L homeolog Kit ELISA, transforming growth factor, beta 2 Kit ELISA, transforming growth factor, beta receptor 2 Kit ELISA, TGFB2 Kit ELISA, tgfb2.L Kit ELISA, Tgfb2 Kit ELISA, Tgfbr2 Kit ELISA, tgfb2 Kit ELISA

Sujet:

Protein Function: TGF-beta 2 has suppressive effects on interleukin-2 dependent T-cell growth.

Background: Transforming growth factor-beta 2(TGF-beta 2) is a secreted protein known as a cytokine that performs many cellular functions and has a vital role during embryonic development. This gene is mapped to 1q41. It is an extracellular glycosylated protein. It is known to suppress the effects of interleukin dependent T-cell tumors. TGF-beta 2 is present at elevated levels in the aqueous humor of patients with primary open angle glaucoma(POAG). Studies have shown that TGF-beta 2 influences cultured trabecular meshwork cells, and it reduced outflow facility when perfused into cultured horse equine anterior segments. In POAG, elevated expression of Gremlin by TM cells inhibited BMP4 antagonism of TGF-beta 2 and led to increased extracellular matrix deposition and elevated IOP.

Synonyms: Transforming growth factor beta-2,TGF-beta-2,BSC-1 cell growth inhibitor,Cetermin,Glioblastoma-derived T-cell suppressor factor,G-TSF,Polyergin,Latency-associated peptide,LAP,TGFB2,

Full Gene Name: Transforming growth factor beta-2

Cellular Localisation: Secreted.

UniProt: P61812

Pathways: Cell-Cell Junction Organization, Production of Molecular Mediator of Immune Response, Protein targeting to Nucleus