SERPINA7 Kit ELISA

N° du produit ABIN5510681

Détail du produit SERPINA7 Kit ELISA

Antigène: SERPINA7 (Serpin Family A Member 7 (SERPINA7))

Épitope: AA 21-415

Reactivité: Humain

Méthode de détection: Colorimetric

Type de méthode: Sandwich ELISA

Application: ELISA

Fonction: Sandwich High Sensitivity ELISA kit for Quantitative Detection of Human Serpin A7

Marque: PicoKine™

Analytical Method: Quantitative

Specificité: Expression system for standard: NSO
Immunogen sequence: A21-A415

Réactivité croisée (Details): There is no detectable cross-reactivity with other relevant proteins.

Attributs du produit:

Tissue Specificity: Expressed by the liver and secreted in plasma.

Information d'application

Plaque: Pre-coated

Restrictions: For Research Use only

Stockage

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)

Date de péremption: 12 months

Détail du antigène

Antigène: SERPINA7 (Serpin Family A Member 7 (SERPINA7))

Autre désignation: SERPINA7 (SERPINA7 Produits)

Synonymes: C730040N12Rik Kit ELISA, Tbg Kit ELISA, TBG Kit ELISA, THYROXINE-BINDING GLOBULIN Kit ELISA, serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7 Kit ELISA, serpin family A member 7 Kit ELISA, Serpina7 Kit ELISA, SERPINA7 Kit ELISA

Sujet:

Protein Function: Major thyroid hormone transport protein in serum.

Background: Thyroxine-binding globulin (TBG), also known as SERPINA7, is the major thyroid hormone transport protein in serum. There are three proteins including thyroxine-binding globulin (TBG), transthyretin and albumin responsible for carrying the thyroid hormones thyroxine (T4) and 3,5,3'-triiodothyronine (T3) in the bloodstream. This gene belongs to the serpin family in genomics, but the protein has no inhibitory function like many other members of the serpin family. Mutations in this gene result in TGB deficiency, which has been classified as partial deficiency, complete deficiency, and excess, based on the level of serum TBG. Alternatively spliced transcript variants encoding different isoforms have been found, but the full-length nature of these variants has not been determined. Using DNA blot hybridization, it is detected that there is a single-copy TBG gene located on the long arm of the X chromosome.

Synonyms: Thyroxine-binding globulin,Serpin A7,T4-binding globulin,SERPINA7,TBG,

Full Gene Name: Thyroxine-binding globulin

Cellular Localisation: Secreted.

UniProt: P05543

Pathways: Hormone Transport