ACVRL1 Kit ELISA
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- Antigène Voir toutes ACVRL1 Kits ELISA
- ACVRL1 (Activin A Receptor Type II-Like 1 (ACVRL1))
- Épitope
- AA 22-118
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Reactivité
- Humain
- Méthode de détection
- Colorimetric
- Type de méthode
- Sandwich ELISA
- Application
- ELISA
- Fonction
- Sandwich High Sensitivity ELISA kit for Quantitative Detection of Human ALK-1/ACVRL1
- Marque
- PicoKine™
- Analytical Method
- Quantitative
- Specificité
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Expression system for standard: NSO
Immunogen sequence: D22-Q118 - Réactivité croisée (Details)
- There is no detectable cross-reactivity with other relevant proteins.
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- Plaque
- Pre-coated
- Restrictions
- For Research Use only
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- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)
- Date de péremption
- 12 months
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- Antigène Voir toutes ACVRL1 Kits ELISA
- ACVRL1 (Activin A Receptor Type II-Like 1 (ACVRL1))
- Autre désignation
- ACVRL1 (ACVRL1 Produits)
- Synonymes
- ACVRL1 Kit ELISA, vgb Kit ELISA, alk1 Kit ELISA, zehn1109 Kit ELISA, hm:zehn1109 Kit ELISA, ACVRLK1 Kit ELISA, ALK-1 Kit ELISA, ALK1 Kit ELISA, HHT Kit ELISA, HHT2 Kit ELISA, ORW2 Kit ELISA, SKR3 Kit ELISA, TSR-I Kit ELISA, R-3 Kit ELISA, R3 Kit ELISA, SETHKIR Kit ELISA, AI115505 Kit ELISA, AI427544 Kit ELISA, Acvrlk1 Kit ELISA, Alk1 Kit ELISA, activin A receptor like type 1 Kit ELISA, activin A receptor type II-like 1 Kit ELISA, activin A receptor, type II-like 1 Kit ELISA, ACVRL1 Kit ELISA, acvrl1 Kit ELISA, Acvrl1 Kit ELISA
- Sujet
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Protein Function: Type I receptor for TGF-beta family ligands BMP9/GDF2 and BMP10 and important regulator of normal blood vessel development. On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. May bind activin as well. .
Background: Serine/threonine-protein kinase receptor R3 is an enzyme that in humans is encoded by the ACVRL1 gene. It is also known as activin receptor-like kinase 1, or ALK1. This gene encodes a type I cell-surface receptor for the TGF-beta superfamily of ligands. It shares with other type I receptors a high degree of similarity in serine-threonine kinase subdomains, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail. The encoded protein shares similar domain structures with other closely related ALK or activin receptor-like kinase proteins that form a subfamily of receptor serine/threonine kinases. Mutations in this gene are associated with hemorrhagic telangiectasia type 2, also known as Rendu-Osler-Weber syndrome 2.
Synonyms: Serine/threonine-protein kinase receptor R3,SKR3,2.7.11.30,Activin receptor-like kinase 1,ALK-1,TGF-B superfamily receptor type I,TSR-I,ACVRL1,ACVRLK1, ALK1,
Full Gene Name: Serine/threonine-protein kinase receptor R3
Cellular Localisation: Cell membrane, Single-pass type I membrane protein. - UniProt
- P37023
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