ICAM5 Kit ELISA
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- ICAM5 (Intercellular Adhesion Molecule 5 (ICAM5))
- Épitope
- AA 28-570
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Reactivité
- Humain
- Méthode de détection
- Colorimetric
- Type de méthode
- Sandwich ELISA
- Application
- ELISA
- Fonction
- Sandwich High Sensitivity ELISA kit for Quantitative Detection of Human ICAM5
- Marque
- PicoKine™
- Analytical Method
- Quantitative
- Specificité
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Expression system for standard: NSO
Immunogen sequence: A28-E570 - Réactivité croisée (Details)
- There is no detectable cross-reactivity with other relevant proteins.
- Attributs du produit
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Tissue Specificity: Expressed on neurons in the most rostral segment of the mammalian brain, the telencephalon.
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- Plaque
- Pre-coated
- Restrictions
- For Research Use only
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- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)
- Date de péremption
- 12 months
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- Antigène Voir toutes ICAM5 Kits ELISA
- ICAM5 (Intercellular Adhesion Molecule 5 (ICAM5))
- Autre désignation
- ICAM5 (ICAM5 Produits)
- Sujet
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Protein Function: ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2).
Background: Intercellular adhesion molecule 5 is a protein that in humans is encoded by the ICAM5 gene. The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is expressed on the surface of telencephalic neurons and displays two types of adhesion activity, homophilic binding between neurons and heterophilic binding between neurons and leukocytes. It may be a critical component in neuron-microglial cell interactions in the course of normal development or as part of neurodegenerative diseases.
Synonyms: Intercellular adhesion molecule 5,ICAM-5,Telencephalin,ICAM5,TLCN, TLN,
Full Gene Name: Intercellular adhesion molecule 5
Cellular Localisation: Membrane, Single-pass type I membrane protein. - UniProt
- Q9UMF0
- Pathways
- Cell-Cell Junction Organization, ER-Nucleus Signaling, Maintenance of Protein Location
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