GREM2 Kit ELISA

N° du produit ABIN5510697

Détail du produit GREM2 Kit ELISA

Antigène: GREM2 (Gremlin 2 (GREM2))

Épitope: AA 22-168

Reactivité: Souris

Méthode de détection: Colorimetric

Type de méthode: Sandwich ELISA

Application: ELISA

Fonction: Sandwich High Sensitivity ELISA kit for Quantitative Detection of Mouse GREM2

Marque: PicoKine™

Analytical Method: Quantitative

Specificité: Expression system for standard: E.coli
Immunogen sequence: R22-Q168

Réactivité croisée (Details): There is no detectable cross-reactivity with other relevant proteins.

Attributs du produit:

Tissue Specificity: Highly expressed in the ovary, followed by brain, spleen, colon, kidney and uterus. In ovary expressed in granulosa cells of selective early antral follicles. .

Information d'application

Plaque: Pre-coated

Restrictions: For Research Use only

Stockage

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)

Date de péremption: 12 months

Détail du antigène

Antigène: GREM2 (Gremlin 2 (GREM2))

Autre désignation: Grem2 (GREM2 Produits)

Synonymes: prdc Kit ELISA, zgc:112207 Kit ELISA, RGD1560008 Kit ELISA, Gremlin2 Kit ELISA, Prdc Kit ELISA, CKTSF1B2 Kit ELISA, DAND3 Kit ELISA, PRDC Kit ELISA, gremlin 2, DAN family BMP antagonist Kit ELISA, gremlin 2, DAN family BMP antagonist b Kit ELISA, gremlin 2, cysteine knot superfamily Kit ELISA, GREM2 Kit ELISA, grem2b Kit ELISA, grem2 Kit ELISA, Grem2 Kit ELISA

Sujet:

Protein Function: Cytokine that inhibits the activity of BMP2 and BMP4 in a dose-dependent manner, and thereby modulates signaling by BMP family members. Contributes to the regulation of embryonic morphogenesis via BMP family members. Antagonizes BMP4-induced suppression of progesterone production in granulosa cells. .

Background: GREM2, also known as PRDC, is one of several BMP antagonists that regulate the functions of BMPs during embryonic development and tissue differentiation. BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted glycosylated protein encoded by this gene is likely due to its direct binding to BMP proteins. The PRDC gene is mapped to chromosome 1q43.

Synonyms: Gremlin-2,Cysteine knot superfamily 1, BMP antagonist 2,Protein related to DAN and cerberus,PRDC,Grem2,Cktsf1b2, Prdc,

Full Gene Name: Gremlin-2

Cellular Localisation: Secreted.

UniProt: O88273