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GREM2 Kit ELISA

GREM2 Reactivité: Humain AA 22-168 Colorimetric Sandwich ELISA
N° du produit ABIN5510698
  • Antigène Voir toutes GREM2 Kits ELISA
    GREM2 (Gremlin 2 (GREM2))
    Épitope
    AA 22-168
    Reactivité
    • 3
    • 2
    • 1
    • 1
    Humain
    Méthode de détection
    Colorimetric
    Type de méthode
    Sandwich ELISA
    Application
    ELISA
    Fonction
    Sandwich High Sensitivity ELISA kit for Quantitative Detection of Human GREM2
    Marque
    PicoKine™
    Analytical Method
    Quantitative
    Specificité
    Expression system for standard: E.coli
    Immunogen sequence: R22-Q168
    Réactivité croisée (Details)
    There is no detectable cross-reactivity with other relevant proteins.
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  • Plaque
    Pre-coated
    Restrictions
    For Research Use only
  • Stock
    4 °C,-20 °C
    Stockage commentaire
    Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)
    Date de péremption
    12 months
  • Antigène Voir toutes GREM2 Kits ELISA
    GREM2 (Gremlin 2 (GREM2))
    Autre désignation
    GREM2 (GREM2 Produits)
    Synonymes
    prdc Kit ELISA, zgc:112207 Kit ELISA, RGD1560008 Kit ELISA, Gremlin2 Kit ELISA, Prdc Kit ELISA, CKTSF1B2 Kit ELISA, DAND3 Kit ELISA, PRDC Kit ELISA, gremlin 2, DAN family BMP antagonist Kit ELISA, gremlin 2, DAN family BMP antagonist b Kit ELISA, gremlin 2, cysteine knot superfamily Kit ELISA, GREM2 Kit ELISA, grem2b Kit ELISA, grem2 Kit ELISA, Grem2 Kit ELISA
    Sujet

    Protein Function: Cytokine that inhibits the activity of BMP2 and BMP4 in a dose-dependent manner, and thereby modulates signaling by BMP family members. Contributes to the regulation of embryonic morphogenesis via BMP family members. Antagonizes BMP4-induced suppression of progesterone production in granulosa cells (By similarity). .

    Background: GREM2, also known as PRDC, is one of several BMP antagonists that regulate the functions of BMPs during embryonic development and tissue differentiation. BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted glycosylated protein encoded by this gene is likely due to its direct binding to BMP proteins. The PRDC gene is mapped to chromosome 1q43.

    Synonyms: Gremlin-2,Cysteine knot superfamily 1, BMP antagonist 2,DAN domain family member 3,Protein related to DAN and cerberus,GREM2,CKTSF1B2, DAND3, PRDC,

    Full Gene Name: Gremlin-2

    Cellular Localisation: Secreted.
    UniProt
    Q9H772
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