GREM2 Kit ELISA
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- Antigène Voir toutes GREM2 Kits ELISA
- GREM2 (Gremlin 2 (GREM2))
- Épitope
- AA 22-168
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Reactivité
- Singe
- Méthode de détection
- Colorimetric
- Type de méthode
- Sandwich ELISA
- Application
- ELISA
- Fonction
- Sandwich High Sensitivity ELISA kit for Quantitative Detection of monkey primate GREM2
- Marque
- PicoKine™
- Analytical Method
- Quantitative
- Specificité
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Expression system for standard: E.coli
Immunogen sequence: R22-Q168 - Réactivité croisée (Details)
- There is no detectable cross-reactivity with other relevant proteins.
- Top Product
- Discover our top product GREM2 Kit ELISA
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- Plaque
- Pre-coated
- Restrictions
- For Research Use only
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- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)
- Date de péremption
- 12 months
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- Antigène Voir toutes GREM2 Kits ELISA
- GREM2 (Gremlin 2 (GREM2))
- Autre désignation
- GREM2 (GREM2 Produits)
- Sujet
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Protein Function: Cytokine that inhibits the activity of BMP2 and BMP4 in a dose-dependent manner, and thereby modulates signaling by BMP family members. Contributes to the regulation of embryonic morphogenesis via BMP family members. Antagonizes BMP4-induced suppression of progesterone production in granulosa cells (By similarity). .
Background: GREM2, also known as PRDC, is one of several BMP antagonists that regulate the functions of BMPs during embryonic development and tissue differentiation. BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted glycosylated protein encoded by this gene is likely due to its direct binding to BMP proteins. The PRDC gene is mapped to chromosome 1q43.
Synonyms: Gremlin-2,Cysteine knot superfamily 1, BMP antagonist 2,DAN domain family member 3,Protein related to DAN and cerberus,GREM2,CKTSF1B2, DAND3, PRDC,
Full Gene Name: Gremlin-2
Cellular Localisation: Secreted. - UniProt
- Q9H772
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