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GDF2 Kit ELISA

GDF2 Reactivité: Humain AA 320-429 Colorimetric Sandwich ELISA
N° du produit ABIN5510718
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    GDF2 (Growth Differentiation Factor 2 (GDF2))
    Épitope
    AA 320-429
    Reactivité
    • 8
    • 8
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Humain
    Méthode de détection
    Colorimetric
    Type de méthode
    Sandwich ELISA
    Application
    ELISA
    Fonction
    Sandwich High Sensitivity ELISA kit for Quantitative Detection of Human BMP-9
    Marque
    PicoKine™
    Analytical Method
    Quantitative
    Specificité
    Expression system for standard: CHO, Immunogen sequence: S320-R429
    Réactivité croisée (Details)
    There is no detectable cross-reactivity with other relevant proteins.
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  • Plaque
    Pre-coated
    Restrictions
    For Research Use only
  • Stock
    4 °C,-20 °C
    Stockage commentaire
    Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)
    Date de péremption
    12 months
  • Antigène Voir toutes GDF2 Kits ELISA
    GDF2 (Growth Differentiation Factor 2 (GDF2))
    Autre désignation
    GDF2 (GDF2 Produits)
    Synonymes
    bmp9 Kit ELISA, BMP-9 Kit ELISA, BMP9 Kit ELISA, Bmp9 Kit ELISA, DSL1 Kit ELISA, growth differentiation factor 2 Kit ELISA, gdf2 Kit ELISA, GDF2 Kit ELISA, Gdf2 Kit ELISA
    Sujet

    Protein Function: Potent circulating inhibitor of angiogenesis. Could be involved in bone formation. Signals through the type I activin receptor ACVRL1 but not other Alks. Signaling through SMAD1 in endothelial cells requires TGF-beta coreceptor endoglin/ENG.

    Background: Growth differentiation factor 2 (GDF2) also known as bone morphogenetic protein (BMP)-9 is a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates cartilage and bone development, angiogenesis and differentiation of cholinergic central nervous system neurons. Homozygous null mice exhibit malformations of the vasculature and skeleton.

    Synonyms: Growth/differentiation factor 2, GDF-2, Bone morphogenetic protein 9, BMP-9, GDF2, BMP9,

    Full Gene Name: growth differentiation factor 2

    Cellular Localisation: Secreted
    UniProt
    Q9UK05
    Pathways
    Transition Metal Ion Homeostasis
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