GDF2 Kit ELISA
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- GDF2 (Growth Differentiation Factor 2 (GDF2))
- Épitope
- AA 319-428
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Reactivité
- Souris
- Méthode de détection
- Colorimetric
- Type de méthode
- Sandwich ELISA
- Application
- ELISA
- Fonction
- Sandwich High Sensitivity ELISA kit for Quantitative Detection of Mouse BMP-9
- Marque
- PicoKine™
- Analytical Method
- Quantitative
- Specificité
- Expression system for standard: CHO, Immunogen sequence: S319-R428
- Réactivité croisée (Details)
- There is no detectable cross-reactivity with other relevant proteins.
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- Plaque
- Pre-coated
- Restrictions
- For Research Use only
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- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)
- Date de péremption
- 12 months
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- Antigène Voir toutes GDF2 Kits ELISA
- GDF2 (Growth Differentiation Factor 2 (GDF2))
- Autre désignation
- Gdf2 (GDF2 Produits)
- Synonymes
- bmp9 Kit ELISA, BMP-9 Kit ELISA, BMP9 Kit ELISA, Bmp9 Kit ELISA, DSL1 Kit ELISA, growth differentiation factor 2 Kit ELISA, gdf2 Kit ELISA, GDF2 Kit ELISA, Gdf2 Kit ELISA
- Sujet
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Protein Function: Potent circulating inhibitor of angiogenesis. Could be involved in bone formation. Signals through the type I activin receptor ACVRL1 but not other Alks. Signaling through SMAD1 in endothelial cells requires TGF-beta coreceptor endoglin/ENG.
Background: Growth differentiation factor 2 (GDF2) also known as bone morphogenetic protein (BMP)-9 is a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates cartilage and bone development, angiogenesis and differentiation of cholinergic central nervous system neurons. Homozygous null mice exhibit malformations of the vasculature and skeleton.
Synonyms: Growth/differentiation factor 2, GDF-2, Bone morphogenetic protein 9, BMP-9, Gdf2, Bmp9,
Full Gene Name: growth differentiation factor 2
Cellular Localisation: Secreted. - UniProt
- Q9WV56
- Pathways
- Transition Metal Ion Homeostasis
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