PON1 Kit ELISA
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- PON1 (Paraoxonase 1 (PON1))
- Épitope
- AA 30-355
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Reactivité
- Souris
- Méthode de détection
- Colorimetric
- Type de méthode
- Sandwich ELISA
- Application
- ELISA
- Fonction
- Sandwich High Sensitivity ELISA kit for Quantitative Detection of Mouse PON1
- Marque
- PicoKine™
- Analytical Method
- Quantitative
- Specificité
- Expression system for standard: E.Coli, Immunogen sequence: A30-L355
- Réactivité croisée (Details)
- There is no detectable cross-reactivity with other relevant proteins.
- Attributs du produit
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Tissue Specificity: Plasma, liver, kidney, heart, brain, small intestine and lung. In the plasma, associated with HDL.
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- Discover our top product PON1 Kit ELISA
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- Plaque
- Pre-coated
- Restrictions
- For Research Use only
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- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)
- Date de péremption
- 12 months
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- Antigène Voir toutes PON1 Kits ELISA
- PON1 (Paraoxonase 1 (PON1))
- Autre désignation
- Pon1 (PON1 Produits)
- Sujet
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Protein Function: Hydrolyzes the toxic metabolites of a variety of organophosphorus insecticides. Capable of hydrolyzing a broad spectrum of organophosphate substrates and lactones, and a number of aromatic carboxylic acid esters. Mediates an enzymatic protection of low density lipoproteins against oxidative modification.
Background: Serum paraoxonase/arylesterase 1 (PON1) also known as aromatic esterase 1 or serum aryldialkylphosphatase 1 is an enzyme that in humans is encoded by the PON1 gene. The PON gene was mapped to chromosome 7q21-q22, and the mouse Pon1 gene was mapped to the proximal end of chromosome 6. PON1 is responsible for hydrolysing organophosphate pesticides and nerve gasses. Polymorphisms in the PON1 gene significantly affect the catalytic ability of the enzyme. PON1 (paraoxonase 1) is also a major anti-atherosclerotic component of high-density lipoprotein (HDL).
Synonyms: Serum paraoxonase/arylesterase 1, PON 1, 3.1.1.2
Full Gene Name: paraoxonase 1
Cellular Localisation: Secreted, extracellular space. - UniProt
- P52430
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