Granulin Kit ELISA

N° du produit ABIN5564195

Détail du produit Granulin Kit ELISA

Antigène: Granulin (GRN)

Reactivité: Rat

Méthode de détection: Colorimetric

Type de méthode: Sandwich ELISA

Gamme de detection: 0.063-4 ng/mL

Seuil minimal de détection: 0.063 ng/mL

Application: ELISA

Type d'échantillon: Cell Culture Supernatant, Serum

Analytical Method: Quantitative

Specificité: Detects rat progranulin.

Réactivité croisée: Rat (Rattus)

Aucune reactivité croisée: Humain

Réactivité croisée (Details): Does not cross-react with human progranulin.

Sensibilité: 40 pg/mL

Attributs du produit: Progranulin (rat) ELISA Kit

Information d'application

Plaque: Pre-coated

Restrictions: For Research Use only

Stockage

Stock: 4 °C

Stockage commentaire: Short Term Storage: +4°C
Long Term Storage: +4°C
12 months after the day of manufacturing. See expiry date on ELISA Kit box.

Détail du antigène

Antigène: Granulin (GRN)

Autre désignation: Progranulin (GRN Produits)

Classe de substances: Viral Protein

Sujet: Progranulin (PGRN) is a widely expressed pluripotent growth factor which plays a role in processes such as development, wound repair and inflammation by activating signaling cascades that control cell cycle progression and cell motility. Its function in the central nervous system is of interest, as mutations in the PGRN gene were found in cases of frontotemporal degeneration (FTLD). In addition, PGRN has also been linked to tumorigenesis. New cutting-edge publications have shown that progranulin might be a biomarker not only for FTLD, but also for other types of Alzheimer's disease (AD). This new data even supposes the potential of progranulin to be a biomarker for MCI (Mild Cognitive Impairment), which would be a hallmark in AD research. Additionally, PGRN is described as a new ligand of TNF receptors and a potential therapeutic against inflammatory disease like arthritis.

UniProt: P23785