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CRLF2 Kit ELISA

CRLF2 Reactivité: Souris AA 20-233 Colorimetric Sandwich ELISA 125 pg/mL - 8000 pg/mL Cell Culture Supernatant, Plasma (EDTA - heparin), Serum
N° du produit ABIN5692222
  • Antigène Voir toutes CRLF2 Kits ELISA
    CRLF2 (Cytokine Receptor-Like Factor 2 (CRLF2))
    Épitope
    AA 20-233
    Reactivité
    • 5
    • 1
    Souris
    Méthode de détection
    Colorimetric
    Type de méthode
    Sandwich ELISA
    Gamme de detection
    125 pg/mL - 8000 pg/mL
    Seuil minimal de détection
    125 pg/mL
    Application
    ELISA
    Fonction
    Sandwich High Sensitivity ELISA kit for Quantitative Detection of Mouse CRLF2. 96wells/kit, with removable strips.
    Marque
    PicoKine™
    Type d'échantillon
    Cell Culture Supernatant, Plasma (EDTA - heparin), Serum
    Analytical Method
    Quantitative
    Specificité
    Expression system for standard: NSO, Immunogen sequence: A20-L233
    Sensibilité
    < 10 pg/mL
    Ingrédients
    96-well plate precoated with antibody
    lyophilized recombinant standard
    biotinylated antibody (dilution 1:100)
    Avidin-Biotin-Peroxidase Complex(ABC)(dilution 1:100)
    Sample diluent buffer
    Antibody diluent buffer
    ABC diluent buffer
    TMB color developing agent
    TMB stop solution
    Adhesive cover
    Top Product
    Discover our top product CRLF2 Kit ELISA
  • Durée du test
    15 min
    Plaque
    Pre-coated
    Restrictions
    For Research Use only
  • Stock
    4 °C,-20 °C
    Stockage commentaire
    Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)
    Date de péremption
    12 months
  • Antigène Voir toutes CRLF2 Kits ELISA
    CRLF2 (Cytokine Receptor-Like Factor 2 (CRLF2))
    Autre désignation
    Crlf2 (CRLF2 Produits)
    Synonymes
    CRLF2 Kit ELISA, CRL2 Kit ELISA, CRLF2Y Kit ELISA, TSLPR Kit ELISA, CRLM2 Kit ELISA, Ly114 Kit ELISA, Tpte2 Kit ELISA, Tslpr Kit ELISA, Crl2 Kit ELISA, cytokine receptor like factor 2 Kit ELISA, cytokine receptor-like factor 2 Kit ELISA, CRLF2 Kit ELISA, Crlf2 Kit ELISA
    Sujet

    Synonyms: Cytokine receptor-like factor 2, Cytokine receptor-like molecule 2, CRLM-2, Thymic stromal lymphopoietin protein receptor, TSLP receptor, Type I cytokine receptor delta 1, Crlf2, Crlm2, Tpte2, Tslpr

    Tissue Specificity: High level of expression in liver, lung and testis. Also expressed in heart, brain, spleen, thymus and bone marrow. Highly expressed in progenitors and myeloid cells. Isoform 2 is expressed in primary hemotopoietic cells.

    Background: Cytokine receptor-like factor 2, also known as TSLPR or CRL2, is a protein that in humans is encoded by the CRLF2 gene. It is mapped to Xp22.33. The protein encoded by this gene is a receptor for thymic stromal lymphopoietin(TSLP). Together with the interleukin 7 receptor(IL7R), the encoded protein and TSLP activate STAT3, STAT5, and JAK2 pathways, which control processes such as cell proliferation and development of the hematopoietic system. Two transcript variants encoding different isoforms have been found for this gene. In addition to it, it has been found that rearrangement of CRLF2 and JAK mutation together contribute to leukemogenesis in B-progenitor ALL.

    Cellular Localisation: Isoform 1: Cell membrane, Single-pass type I membrane protein.
    UniProt
    Q8CII9
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