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IL6RA Kit ELISA

IL6RA Reactivité: Humain Colorimetric Sandwich ELISA 31.2 pg/mL - 2000 pg/mL Cell Culture Supernatant, Plasma (EDTA - heparin - citrate), Serum
N° du produit ABIN6719752
  • Antigène Voir toutes IL6RA Kits ELISA
    IL6RA (Interleukin 6 Receptor, alpha (IL6RA))
    Reactivité
    • 2
    • 1
    Humain
    Méthode de détection
    Colorimetric
    Type de méthode
    Sandwich ELISA
    Gamme de detection
    31.2 pg/mL - 2000 pg/mL
    Seuil minimal de détection
    31.2 pg/mL
    Application
    ELISA
    Fonction
    Sandwich ELISA for Quantitative Detection of Antigen
    Type d'échantillon
    Cell Culture Supernatant, Plasma (EDTA - heparin - citrate), Serum
    Analytical Method
    Quantitative
    Attributs du produit

    Synonyms: CD126, CD126 antigen, Gp80, IL 6R 1, IL 6R alpha, IL-6 receptor subunit alpha, IL-6R 1, IL-6R subunit alpha, IL-6R-1, IL-6R-alpha, IL-6RA, Il6r, IL6R1, IL6RA, IL6RA_HUMAN, IL6Ralpha, Interleukin 6 receptor, Interleukin 6 receptor alpha chain, Interleukin-6 receptor subunit alpha, Membrane glycoprotein 80, MGC104991, OTTHUMP00000034320

    Background: IL6R alpha(IL6RA) also known as CD126 or IL6R, is a type I cytokine receptor. The IL6 receptor is a protein complex consisting of a IL-6 receptor subunit(IL6R) and interleukin 6 signal transducer Glycoprotein 130. IL6R also denotes the human gene encoding this subunit. Alternatively spliced transcript variants encoding distinct isoforms have been reported. IL6R subunit is also shared by many other cytokines. Interleukin-6 receptor has been shown to interact with Interleukin 6 and Ciliary neurotrophic factor. Ligand binding did not appear to affect IL6R dimerization status. IL6R dimerization occurs both on the cell surface and in solution.

    Gene Name: IL6R

    Production: Natural and recombinant human IL-6R alpha. There is no detectable cross-reactivity with other relevant proteins.

    Standard: Expression system for standard: sf21, Immunogen sequence: L20-D358

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  • Indications d'application

    Application Note: Useful in Sandwich ELISA for Quantitative Detection of Antigen. Aliquot 0.1 mL per well of the 2000pg/mL, 1000pg/mL, 500pg/mL, 250pg/mL, 125pg/mL, 62.5pg/mL, 31.2pg/mL human IL-6R alpha standard solutions into the precoated 96-well plate. Add 0.1 mL of the sample diluent buffer into the control well (Zero well). Add 0.1 mL of each properly diluted sample of human cell culture supernates, serum, plasma(heparin, EDTA, citrate) or urine to each empty well. It is recommended that each human IL-6R alpha standard solution and each sample be measured in duplicate.

    Blood Product Anticoagulant: Heparin Sodium

    ELISA Dilution: 31.2pg/mL-2000pg/mL

    Volume d'échantillon
    100 μL
    Plaque
    Pre-coated
    Restrictions
    For Research Use only
  • Stock
    RT,4 °C,-20 °C
    Stockage commentaire
    Store vials at 4°C prior to opening. Centrifuge product if not completely clear after standing at room temperature. This product is stable for 6 months at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage freeze at -20°C or below for 12 months. Avoid cycles of freezing and thawing.
  • Antigène Voir toutes IL6RA Kits ELISA
    IL6RA (Interleukin 6 Receptor, alpha (IL6RA))
    Autre désignation
    IL-6R alpha (IL6RA Produits)
    Synonymes
    IL6R1 Kit ELISA, Il6ra Kit ELISA, CD126 Kit ELISA, IL-6R-1 Kit ELISA, IL-6RA Kit ELISA, IL6Q Kit ELISA, IL6RA Kit ELISA, IL6RQ Kit ELISA, gp80 Kit ELISA, IL-6R Kit ELISA, Il6r Kit ELISA, interleukin 6 receptor Kit ELISA, interleukin 6 receptor, alpha Kit ELISA, Il6r Kit ELISA, IL6R Kit ELISA, Il6ra Kit ELISA
    ID gène
    3570
    NCBI Accession
    NP_000556
    UniProt
    A0N0L5
    Pathways
    Signalistation JAK/STAT, Autophagy, Growth Factor Binding, Cancer Immune Checkpoints
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