BMP4 Kit ELISA
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- Antigène Voir toutes BMP4 Kits ELISA
- BMP4 (Bone Morphogenetic Protein 4 (BMP4))
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Reactivité
- Humain
- Méthode de détection
- Colorimetric
- Type de méthode
- Sandwich ELISA
- Gamme de detection
- 62.5 pg/mL - 4000 pg/mL
- Seuil minimal de détection
- 62.5 pg/mL
- Application
- ELISA
- Fonction
- Sandwich ELISA for Quantitative Detection of Antigen
- Type d'échantillon
- Bone, Cell Culture Supernatant
- Analytical Method
- Quantitative
- Attributs du produit
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Synonyms: BMP 2B, BMP 4, BMP2B, BMP2B1, BOMPR4A, Bone morphogenetic protein 2B, Bone morphogenetic protein 4, DVR4, OTTMUSP00000021065, OTTMUSP00000021066, ZYME
Background: Bone morphogenetic protein 4 is a protein that in humans is encoded by the BMP4 gene which is located to 14q22-q23.1, The protein encoded by this gene is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. BMP4 is a polypeptide belonging to the TGF-beta superfamily of proteins. It, like other bone morphogenetic proteins, is involved in bone and cartilage development, specifically tooth and limb development and fracture repair. It has been shown to be involved in muscle development, bone mineralization, and uteric bud development. BMP4 has also been implicated in Fibrodysplasia Ossificans Progressiva in which it is underexpressed. In human embryonic development, BMP4 is a critical signaling molecule required for the early differentiation of the embryo and establishing of a dorsal-ventral axis. BMP4 is secreted from the dorsal portion of the notochord, and it acts in concert with sonic hedgehog(released from the ventral portion of the notochord) to establish a dorsal-ventral axis for the differentiation of later structures. BMP4 stimulates differentiation of overlying ectodermal tissue. Inhibition of the BMP4 signal(by chordin, noggin, or follistatin) causes the ectoderm to differentiate into the neural plate. The standard product used in this kit is recombinant BMP-4 with the molecular mass of 26KDa.
Gene Name: BMP4
Production: Natural and recombinant human BMP-4. There is no detectable cross-reactivity with other relevant proteins.
Standard: Expression system for standard: NSO, Immunogen sequence: S293-R408
- Top Product
- Discover our top product BMP4 Kit ELISA
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- Indications d'application
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Application Note: Useful in Sandwich ELISA for Quantitative Detection of Antigen. Aliquot 0.1 mL per well of the 4000pg/mL, 2000pg/mL,1000pg/mL, 500pg/mL, 250pg/mL, 125pg/mL, 62.5pg/mL human BMP-4 standard solutions into the precoated 96-well plate. Add 0.1 mL of the sample diluent buffer into the control well (Zero well). Add 0.1 mL of each properly diluted sample of human bone tissue or cell culture supernates to each empty well. It is recommended that each human BMP-4 standard solution and each sample be measured in duplicate.
ELISA Dilution: 62.5pg/mL-4000pg/mL
- Volume d'échantillon
- 100 μL
- Plaque
- Pre-coated
- Restrictions
- For Research Use only
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- Stock
- RT,4 °C,-20 °C
- Stockage commentaire
- Store vials at 4°C prior to opening. Centrifuge product if not completely clear after standing at room temperature. This product is stable for 6 months at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage freeze at -20°C or below for 12 months. Avoid cycles of freezing and thawing.
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- Antigène Voir toutes BMP4 Kits ELISA
- BMP4 (Bone Morphogenetic Protein 4 (BMP4))
- Autre désignation
- BMP-4 (BMP4 Produits)
- Synonymes
- BMP2B Kit ELISA, BMP2B1 Kit ELISA, MCOPS6 Kit ELISA, OFC11 Kit ELISA, ZYME Kit ELISA, Bmp-4 Kit ELISA, Bmp2b Kit ELISA, Bmp2b-1 Kit ELISA, Bmp2b1 Kit ELISA, BOMPR4A Kit ELISA, bmp-4 Kit ELISA, zbmp-4 Kit ELISA, zgc:100779 Kit ELISA, BMP-4 Kit ELISA, XBMP-4 Kit ELISA, bmp2b Kit ELISA, bmp2b1 Kit ELISA, bmp4 Kit ELISA, ofc11 Kit ELISA, xbmp4 Kit ELISA, zyme Kit ELISA, BMP4 Kit ELISA, bone morphogenetic protein 4 Kit ELISA, bone morphogenetic protein 4 L homeolog Kit ELISA, bone morphogenetic protein 4 S homeolog Kit ELISA, BMP4 Kit ELISA, Bmp4 Kit ELISA, bmp4 Kit ELISA, bmp4.L Kit ELISA, bmp4.S Kit ELISA
- ID gène
- 652
- NCBI Accession
- NP_001193
- UniProt
- P12644
- Pathways
- Steroid Hormone Mediated Signaling Pathway, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development
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