LYVE1 Kit ELISA

N° du produit ABIN6719878

Détail du produit LYVE1 Kit ELISA

Antigène: LYVE1 (Lymphatic Vessel Endothelial Hyaluronan Receptor 1 (LYVE1))

Reactivité: Humain

Méthode de détection: Colorimetric

Type de méthode: Sandwich ELISA

Gamme de detection: 31.2 pg/mL - 2000 pg/mL

Seuil minimal de détection: 31.2 pg/mL

Application: ELISA

Fonction: Sandwich ELISA for Quantitative Detection of Antigen

Type d'échantillon: Cell Culture Lysate, Cell Culture Supernatant, Tissue Homogenate

Analytical Method: Quantitative

Attributs du produit:

Synonyms: cell surface retention sequence binding protein-1, Cell surface retention sequence-binding protein 1, CRSBP-1, CRSBP1, extracellular link domain containing 1, extracellular link domain-containing 1, Extracellular link domain-containing protein 1, HAR, Hyaluronic acid receptor, lymphatic vessel endothelial hyaluronan receptor 1, Lymphatic vessel endothelial hyaluronic acid receptor 1, LYVE-1, LYVE1, LYVE1_HUMAN, XLKD1

Background: Extracellular link domain containing 1, also known as LYVE-1 or XLKD1 is a human gene. The International Radiation Hybrid Mapping Consortium mapped the LYVE1 gene to chromosome 11p15.4. This gene encodes a type I integral membrane glycoprotein. The encoded protein acts as a receptor and binds to both soluble and immobilized hyaluronan. This protein may function in lymphatic hyaluronan transport and have a role in tumor metastasis. This gene may play a role in autocrine regulation of cell growth mediated by growth regulators containing cell surface retention sequence binding(CRS). It may act as a hyaluronan(HA) transporter, either mediating its uptake for catabolism within lymphatic endothelial cells themselves, or its transport into the lumen of afferent lymphatic vessels for subsequent re-uptake and degradation in lymph nodes.

Gene Name: LYVE1

Production: Natural and recombinant human LYVE-1. There is no detectable cross-reactivity with other relevant proteins.

Standard: Expression system for standard: NSO, Immunogen sequence: S24-T238

Information d'application

Indications d'application:

Application Note: Useful in Sandwich ELISA for Quantitative Detection of Antigen. Aliquot 0.1 mL per well of the 2000pg/mL, 1000pg/mL, 500pg/mL, 250pg/mL, 125pg/mL, 62.5pg/mL, 31.2pg/mL human LYVE-1 standard solutions into the precoated 96-well plate. Add 0.1 mL of the sample diluent buffer into the control well (Zero well). Add 0.1 mL of each properly diluted sample of human cell culture supernates, cell lysates or tissue homogenates to each empty well. It is recommended that each human LYVE-1 standard solution and each sample be measured in duplicate.

ELISA Dilution: 31.2pg/mL-2000pg/mL

Volume d'échantillon: 100 μL

Plaque: Pre-coated

Restrictions: For Research Use only

Stockage

Stock: RT,4 °C,-20 °C

Stockage commentaire: Store vials at 4°C prior to opening. Centrifuge product if not completely clear after standing at room temperature. This product is stable for 6 months at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage freeze at -20°C or below for 12 months. Avoid cycles of freezing and thawing.

Détail du antigène

Antigène: LYVE1 (Lymphatic Vessel Endothelial Hyaluronan Receptor 1 (LYVE1))

Autre désignation: LYVE-1 (LYVE1 Produits)

Synonymes: LYVE1 Kit ELISA, XLKD1 Kit ELISA, CRSBP-1 Kit ELISA, HAR Kit ELISA, LYVE-1 Kit ELISA, 1200012G08Rik Kit ELISA, Crsbp-1 Kit ELISA, Lyve-1 Kit ELISA, Xlkd1 Kit ELISA, lymphatic vessel endothelial hyaluronic receptor 1a Kit ELISA, lymphatic vessel endothelial hyaluronan receptor 1 Kit ELISA, lyve1a Kit ELISA, LYVE1 Kit ELISA, Lyve1 Kit ELISA

ID gène: 10894

NCBI Accession: NP_006682

UniProt: Q9Y5Y7

Pathways: Glycosaminoglycan Metabolic Process