CD320 Kit ELISA
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- Antigène Voir toutes CD320 Kits ELISA
- CD320 (CD320 Molecule (CD320))
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Reactivité
- Humain
- Méthode de détection
- Colorimetric
- Type de méthode
- Sandwich ELISA
- Gamme de detection
- 156 pg/mL - 10000 pg/mL
- Seuil minimal de détection
- 156 pg/mL
- Application
- ELISA
- Fonction
- Sandwich ELISA for Quantitative Detection of Antigen
- Type d'échantillon
- Cell Culture Lysate, Cell Culture Supernatant, Plasma (EDTA - heparin), Serum, Tissue Homogenate
- Analytical Method
- Quantitative
- Attributs du produit
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Synonyms: 8D6, 8D6 antigen, 8D6A, CD320, CD320 antigen, CD320_HUMAN, FDC-signaling molecule 8D6, FDC-SM-8D6, TCblR, Transcobalamin receptor
Background: CD320(cluster of differentiation 320), also known as 8D6A or TCBLR, is a human gene. It is mapped to chromosome 19p13.2. This gene encodes the transcobalamin receptor that is expressed at the cell surface. It mediates the cellular uptake of transcobalamin bound cobalamin(vitamin B12), and the expression of CD320 enhanced B-cell proliferation and immunoglobulin secretion. Mutations in this gene are associated with methylmalonic aciduria. It has been found that antagonists of the CD320 signaling pathway may counter the growth of follicular lymphomas or other tumors that metastasize to lymphoid follicles. CD320 is also a specific receptor for uptake of TCN2-bound cobalamin.
Gene Name: CD320
Production: Natural and recombinant human CD320. There is no detectable cross-reactivity with other relevant proteins.
Standard: Expression system for standard: NSO, Immunogen sequence: S36-Y229
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- Indications d'application
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Application Note: Useful in Sandwich ELISA for Quantitative Detection of Antigen. Aliquot 0.1 mL per well of the 10,000pg/mL, 5000pg/mL, 2500pg/mL, 1250pg/mL, 625pg/mL, 312pg/mL, 156pg/mL human CD320 standard solutions into the precoated 96-well plate. Add 0.1 mL of the sample diluent buffer into the control well (Zero well). Add 0.1 mL of each properly diluted sample of human cell culture supernates, serum, plasma(heparin, EDTA) or urine to each empty well. It is recommended that each human CD320 standard solution and each sample be measured in duplicate.
Blood Product Anticoagulant: Heparin Sodium
ELISA Dilution: 156pg/mL-10,000pg/mL
- Volume d'échantillon
- 100 μL
- Plaque
- Pre-coated
- Restrictions
- For Research Use only
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- Stock
- RT,4 °C,-20 °C
- Stockage commentaire
- Store vials at 4°C prior to opening. Centrifuge product if not completely clear after standing at room temperature. This product is stable for 6 months at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage freeze at -20°C or below for 12 months. Avoid cycles of freezing and thawing.
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- Antigène Voir toutes CD320 Kits ELISA
- CD320 (CD320 Molecule (CD320))
- Autre désignation
- CD320 - 8D6A (CD320 Produits)
- Synonymes
- 8D6 Kit ELISA, 8D6A Kit ELISA, TCBLR Kit ELISA, 425O18-1 Kit ELISA, D17Ertd716e Kit ELISA, NG29 Kit ELISA, VLDL Kit ELISA, RGD1305860 Kit ELISA, TCblR Kit ELISA, CD320 molecule Kit ELISA, CD320 antigen Kit ELISA, CD320 Kit ELISA, Cd320 Kit ELISA
- ID gène
- 51293
- NCBI Accession
- NP_001159367
- UniProt
- Q9NPF0
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