LOXL2 Kit ELISA

N° du produit ABIN6719903

Détail du produit LOXL2 Kit ELISA

Antigène: LOXL2 (Lysyl Oxidase-Like 2 (LOXL2))

Reactivité: Humain

Méthode de détection: Colorimetric

Type de méthode: Sandwich ELISA

Gamme de detection: 156 pg/mL - 10000 pg/mL

Seuil minimal de détection: 156 pg/mL

Application: ELISA

Fonction: Sandwich ELISA for Quantitative Detection of Antigen

Type d'échantillon: Cell Culture Lysate, Cell Culture Supernatant, Plasma (EDTA - heparin), Serum, Tissue Homogenate

Analytical Method: Quantitative

Attributs du produit:

Synonyms: LOR 2, LOR2, LOX L2, LOXL 2, LOXL2, LOXL2_HUMAN, Lysyl oxidase homolog 2, Lysyl oxidase like 2, Lysyl oxidase like protein 2, Lysyl oxidase related 2, Lysyl oxidase related protein 2, Lysyl oxidase related protein WS9 14, Lysyl oxidase-like protein 2, Lysyl oxidase-related protein 2, Lysyl oxidase-related protein WS9-14, WS9 14

Background: Lysyl oxidase homolog 2 is an enzyme that in humans is encoded by the LOXL2 gene. This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family. LOXL2 can also crosslink collagen type IV and hence influence the sprouting of new blood vessels.

Gene Name: LOXL2

Production: Natural and recombinant human LOXL2. There is no detectable cross-reactivity with other relevant proteins.

Standard: Expression system for standard: NSO, Immunogen sequence: Q26-Q774

Information d'application

Indications d'application:

Application Note: Useful in Sandwich ELISA for Quantitative Detection of Antigen. Aliquot 0.1 mL per well of the 10,000pg/mL, 5000pg/mL, 2500pg/mL, 1250pg/mL, 625pg/mL, 312pg/mL, 156pg/mL human LOXL2 standard solutions into the precoated 96-well plate. Add 0.1 mL of the sample diluent buffer into the control well (Zero well). Add 0.1 mL of each properly diluted sample of human cell culture supernates, cell lysates, tissue homogenates, serum or plasma(heparin, EDTA) to each empty well. It is recommended that each human LOXL2 standard solution and each sample be measured in duplicate.

Blood Product Anticoagulant: Heparin Sodium

ELISA Dilution: 156pg/mL-10,000pg/mL

Volume d'échantillon: 100 μL

Plaque: Pre-coated

Restrictions: For Research Use only

Stockage

Stock: RT,4 °C,-20 °C

Stockage commentaire: Store vials at 4°C prior to opening. Centrifuge product if not completely clear after standing at room temperature. This product is stable for 6 months at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage freeze at -20°C or below for 12 months. Avoid cycles of freezing and thawing.

Détail du antigène

Antigène: LOXL2 (Lysyl Oxidase-Like 2 (LOXL2))

Autre désignation: LOXL2 (LOXL2 Produits)

Synonymes: LOR2 Kit ELISA, WS9-14 Kit ELISA, CG4402 Kit ELISA, Dmel\\CG4402 Kit ELISA, Dmloxl-2 Kit ELISA, dmlox-2 Kit ELISA, 1110004B06Rik Kit ELISA, 4930526G11Rik Kit ELISA, 9430067E15Rik Kit ELISA, GB13360 Kit ELISA, lox2-like Kit ELISA, LOXL2 Kit ELISA, lor2 Kit ELISA, loxl-2 Kit ELISA, ws9-14 Kit ELISA, im:7136137 Kit ELISA, si:dkeyp-32b1.1 Kit ELISA, wu:fk12g04 Kit ELISA, zgc:158414 Kit ELISA, lysyl oxidase like 2 Kit ELISA, lysyl oxidase-like 2 Kit ELISA, lysyl oxidase homolog 4 Kit ELISA, lysyl oxidase like 2 L homeolog Kit ELISA, lysyl oxidase-like 2b Kit ELISA, LOXL2 Kit ELISA, lox2 Kit ELISA, Loxl2 Kit ELISA, LOC408544 Kit ELISA, loxl2.L Kit ELISA, loxl2 Kit ELISA, loxl2b Kit ELISA

ID gène: 4017

NCBI Accession: NP_002309

UniProt: Q9Y4K0

Pathways: Chromatin Binding