CD130/gp130 Kit ELISA
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- Antigène Voir toutes CD130/gp130 (IL6ST) Kits ELISA
- CD130/gp130 (IL6ST) (Interleukin 6 Signal Transducer (Gp130, Oncostatin M Receptor) (IL6ST))
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Reactivité
- Humain
- Méthode de détection
- Colorimetric
- Type de méthode
- Sandwich ELISA
- Gamme de detection
- 125 pg/mL - 8000 pg/mL
- Seuil minimal de détection
- 125 pg/mL
- Application
- ELISA
- Fonction
- Sandwich ELISA for Quantitative Detection of Antigen
- Type d'échantillon
- Cell Culture Supernatant, Plasma (EDTA - heparin - citrate), Serum
- Analytical Method
- Quantitative
- Attributs du produit
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Synonyms: CD130 antigen, CDw130, gp130, IL6 R beta, Interleukin 6 receptor subunit beta, Interleukin 6 signal transducer, Membrane glycoprotein 130, Oncostatin M receptor alpha subunit
Background: GP130(Glycoprotein 130) also known as IL6ST or CD130, is a transmembrane protein which is the founding member of the class of all cytokine receptors. The GP130 gene is mapped on 5q11.2. Gp130 showed an apparent molecular mass of 130 kD by SDS-PAGE. Gp130 is involved in the formation of high-affinity IL6-binding sites and in IL6 signal transduction. Sgp130 has a role in modulating signals transduced by membrane-bound gp130. Gp130 is an important part of many different types of signaling complexes. Gp130 Molecules with mutations in either of these segments could not transduce a growth signal.
Gene Name: IL6ST
Production: Natural and recombinant human Sgp130. There is no detectable cross-reactivity with other relevant proteins.
Standard: Expression system for standard: sf21, Immunogen sequence: L24-E619
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- Indications d'application
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Application Note: Useful in Sandwich ELISA for Quantitative Detection of Antigen. Aliquot 0.1 mL per well of the 8000pg/mL, 4000pg/mL, 2000pg/mL, 1000pg/mL, 500pg/mL, 250pg/mL, 125pg/mL human GP130 standard solutions into the precoated 96-well plate. Add 0.1 mL of the sample diluent buffer into the control well (Zero well). Add 0.1 mL of each properly diluted sample of human cell culture supernates, serum or plasma(heparin, EDTA, citrate) to each empty well. It is recommended that each human GP130 standard solution and each sample be measured in duplicate.
Blood Product Anticoagulant: Heparin Sodium
ELISA Dilution: 125pg/mL-8000pg/mL
- Volume d'échantillon
- 100 μL
- Plaque
- Pre-coated
- Restrictions
- For Research Use only
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- Stock
- RT,4 °C,-20 °C
- Stockage commentaire
- Store vials at 4°C prior to opening. Centrifuge product if not completely clear after standing at room temperature. This product is stable for 6 months at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage freeze at -20°C or below for 12 months. Avoid cycles of freezing and thawing.
-
- Antigène Voir toutes CD130/gp130 (IL6ST) Kits ELISA
- CD130/gp130 (IL6ST) (Interleukin 6 Signal Transducer (Gp130, Oncostatin M Receptor) (IL6ST))
- Autre désignation
- Gp130 - IL6ST (IL6ST Produits)
- Synonymes
- CD130 Kit ELISA, CDW130 Kit ELISA, GP130 Kit ELISA, IL-6RB Kit ELISA, 5133400A03Rik Kit ELISA, AA389424 Kit ELISA, BB405851 Kit ELISA, D13Ertd699e Kit ELISA, gp130 Kit ELISA, Ac1055 Kit ELISA, Gp130 Kit ELISA, Il-6rb Kit ELISA, IL-6 Kit ELISA, interleukin 6 signal transducer Kit ELISA, IL6ST Kit ELISA, Il6st Kit ELISA, il6st Kit ELISA
- ID gène
- 3572
- NCBI Accession
- NP_001177910
- UniProt
- P40189
- Pathways
- Signalistation JAK/STAT, Cellular Glucan Metabolic Process, Autophagy, Smooth Muscle Cell Migration, Cancer Immune Checkpoints
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